Preliminary examination of acceptability, feasibility, and effectiveness of internet-based cognitive behavioral therapy for treatment of depression and anxiety in infertile women

Kheirkhah, Farzan; Faramarzi, Mahbobeh; Shafierizi, Shiva; Chehrazi, Mohammad; Basirat, Zahra

doi:10.1016/j.heliyon.2023.e15760

Cited by 7 publications

(10 citation statements)

References 61 publications

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“…Types of remote CBT included interactive voice response technology, 34 computerized CBT, 39 , 51 , 55 , 58 , 63 telehealth and telephone-based CBT, 44 , 64 , 65 , 67 , 69 , 71 , 72 , 74 , 76 – 79 , 82 – 85 videoconference, 57 , 66 , 68 , 73 , 75 , 86 , 87 and Internet-delivered CBT. 35 – 38 , 40 – 43 , 45 – 54 , 56 , 59 – 62 , 70 , 80 , 81 …”

Section: Resultsmentioning

confidence: 99%

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Therapist-guided remote versus in-person cognitive behavioural therapy: a systematic review and meta-analysis of randomized controlled trials

Zandieh,

Abdollahzadeh,

Sadeghirad

et al. 2024

CMAJ

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Background: Cognitive behavioural therapy (CBT) has been shown to be effective for several psychiatric and somatic conditions; however, most randomized controlled trials (RCTs) have administered treatment in person and whether remote delivery is similarly effective remains uncertain. We sought to compare the effectiveness of therapist-guided remote CBT and in-person CBT. Methods: We systematically searched MEDLINE, Embase, PsycINFO, CINAHL, and the Cochrane Central Register of Controlled Trials from inception to July 4, 2023, for RCTs that enrolled adults (aged ≥ 18 yr) presenting with any clinical condition and that randomized participants to either therapist-guided remote CBT (e.g., teleconference, videoconference) or in-person CBT. Paired reviewers assessed risk of bias and extracted data independently and in duplicate. We performed random-effects model meta-analyses to pool patient-important primary outcomes across eligible RCTs as standardized mean differences (SMDs). We used Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidance to assess the certainty of evidence and used the Instrument to Assess the Credibility of Effect Modification Analyses (ICEMAN) to rate the credibility of subgroup effects. Results: We included 54 RCTs that enrolled a total of 5463 patients. Seventeen studies focused on treatment of anxiety and related disorders, 14 on depressive symptoms, 7 on insomnia, 6 on chronic pain or fatigue syndromes, 5 on body image or eating disorders, 3 on tinnitus, 1 on alcohol use disorder, and 1 on mood and anxiety disorders. Moderate-certainty evidence showed little to no difference in the effectiveness of therapist-guided remote and in-person CBT on primary outcomes (SMD −0.02, 95% confidence interval −0.12 to 0.07). Interpretation: Moderate-certainty evidence showed little to no difference in the effectiveness of in-person and therapist-guided remote CBT across a range of mental health and somatic disorders, suggesting potential for the use of therapist-guided remote CBT to facilitate greater access to evidence-based care. Systematic review registration: Open Science Framework ( https://osf.io/7asrc )

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Section: Resultsmentioning

confidence: 99%

“…Kheirkhah, 2023 70 Ying, 2022 42 Granberg, 2022 73 Milgroma, 2021 41 Watts, 2020 86 Meng, 2019 65 Maieritsch, 2016 66 Lancee, 2016 56 Vallejo, 2015 61 Egede, 2015 76 de Boer, 2014 48 Morland, 2014 87 Glueckauf, 2012 74 Hedman, 2011 50 Andrews, 2011 36 Kaldo, 2008 43 Carlbring, 2005…”

Section: Subgroup DLmentioning

confidence: 99%

Therapist-guided remote versus in-person cognitive behavioural therapy: a systematic review and meta-analysis of randomized controlled trials

Zandieh,

Abdollahzadeh,

Sadeghirad

et al. 2024

CMAJ

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“…Therefore, the proper intervention helps the majority of women facing the couple’s fertility problems to achieve some type of resolution. It has been well-documented that online interventions for infertile individuals can reduce symptoms of anxiety and depression [ 8 , 9 , 51 , 70 ]. Besides, identifying factors that influence response to psychological intervention can be highly beneficial.…”

Section: Discussionmentioning

confidence: 99%

“…The online treatment was administered on the Peaceful Mind website. In previous studies, this program has been demonstrated to be effective for psychological disorders among women facing the couple’s fertility problems [ 8 , 9 ]. The therapist could manage patients’ registration and monitor their activities in the therapist panel.…”

Section: Methodsmentioning

confidence: 99%

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Predictors of nonresponse to treatment and low adherence to internet-based cognitive behavioral therapy in depressed/anxious women facing the couple’s fertility problems: a secondary analysis of a randomized control trial

Shafierizi,

Basirat,

Nasiri-Amiri

et al. 2024

BMC Psychiatry

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Background The study aimed to examine the predictors of treatment nonresponse and low adherence to Internet-based cognitive behavioral therapy and face-to-face therapy for treating depression and anxiety in women facing the couple’s fertility problems. Methods This is a secondary analysis based on a previous randomized controlled trial including 152 depressed/anxious women facing the couple’s fertility problems. The study defines low adherence as receiving less than 4 sessions (out of 8 sessions). Nonresponse to treatment refers to a < 50% reduction in the anxiety and depression total scores. Results A high level of anxiety/depression score before psychotherapy increases the risk of nonresponse to both Internet-based and face-to-face psychotherapies by 1.4 to 2 times in women facing the couple’s fertility problems after the treatment and in the 6-month follow-up. However, 4 factors, including diagnosis of mixed anxiety and depression, low education level, long marriage duration, and infertility caused by mixed female/male factors, reduced the risk of nonresponse to psychotherapies. Conclusion Women facing the couple’s fertility problems with high depression and anxiety scores are at risk of poor prognosis in response to psychotherapy. Psychologists and healthcare providers of infertility centers should pay more attention to the timely identification and referral of depressed/anxious patients to psychologists.

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Digital mental health interventions for the treatment of depression: A multiverse meta-analysis

Plessen,

Panagiotopoulou,

Tong

et al. 2025

Journal of Affective Disorders

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Preliminary examination of acceptability, feasibility, and effectiveness of internet-based cognitive behavioral therapy for treatment of depression and anxiety in infertile women

Cited by 7 publications

References 61 publications

Therapist-guided remote versus in-person cognitive behavioural therapy: a systematic review and meta-analysis of randomized controlled trials

Therapist-guided remote versus in-person cognitive behavioural therapy: a systematic review and meta-analysis of randomized controlled trials

Predictors of nonresponse to treatment and low adherence to internet-based cognitive behavioral therapy in depressed/anxious women facing the couple’s fertility problems: a secondary analysis of a randomized control trial

Digital mental health interventions for the treatment of depression: A multiverse meta-analysis

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