The weak photostability of photochromic dyes applied to textile substrates is one of the disadvantages of the broader use of photochromic dyes in the textile industry. Therefore, the influence of optical brightener concentration on both the photocoloration and photostability of cotton fabric coated with photochromic microcapsules using a pad-dry-cure process, as well as the physical-mechanical properties and colorfastness properties, were studied in this research. Coated samples were subjected to different tests according to valid EN ISO standards; namely mass per unit area, fabric stiffness, breaking force and elongation, air permeability, and different colorfastness properties (rubbing, domestic and commercial laundering, and light). Results showed that the coated fabric had higher mass per unit area, stiffness, breaking force and elongation and lower air permeability compared to uncoated fabric, irrespective of the padding bath composition. Coated fabric has better colorfastness to wet than dry rubbing. The colorfastness to washing decreases with the increased number of washing cycles. The use of optical brightener decreases the photocoloration of coated fabric and increases the photostability of coated fabric after the exposure of samples to a Xenotest apparatus for longer than 12 h. dyes are poorly exhausted on textile substrates [4,6] due to their highly non-planar ring-closed form and the deficiency of substituents, which increases the solubility of the dye in an aqueous medium. Consequently, the poor photochromic color build-up is obtained on textile substrates. Furthermore, the study of the synthesis and application of water-soluble photochromic dyes, and the study of photochromic dye with a reactive anchor are already published [5,8]. Commercial photochromic dyes are often in the form of microcapsules [3], and thus they are applied onto textile substrates by pad-dry-cure processes, coating, or printing [24][25][26] and the photochromic color build-up is more pronounced. Moreover, plasma treatment could even increase the embedment of UV-responsive microcapsules to polyethylene terephthalate fabric during the pad-dry-cure process [27].In ophthalmics, photochromic dyes achieved commercial success, but in the textile industry, they are rarely represented due to poor colorfastness to light and washing [3]. The other reason could lie in the non-conventional dyeing process for their application to textiles, due to the form in which commercial photochromic colorants are supplied [3]. Research carried out so far showed weak photostability of photochromic dyes applied to textiles, which can be improved by the use of UV-absorbers or hindered amine light stabilizers (HALS) [15]. From the study, researchers established that the photostability is strongly dependent on the concentration and structure of the photochromic dye, UV-absorbers, and HALS. The light fatigue resistance of spiropyranes can be also improved by the addition of nickel or zinc 4,8-dihydroxyquionline-2-carboxilated, which causes the stabilization of...