Preliminary Experience Using Full-Spectrum Endoscopy for Colorectal Cancer Screening: Matched Case Controlled Study

Abstract

Background/Aim. High-quality colonoscopy is needed to reduce the morbidity and mortality of colorectal cancer. Full-spectrum endoscopy (FUSE) has recently shown potential in improving adenoma detection during colonoscopy. This study aimed to evaluate the feasibility and utility of FUSE colonoscopy. Methods. From April 2015 to February 2016, 130 patients underwent FUSE colonoscopy for screening at a tertiary cancer center. Cecal intubation rate (CIR), procedure time, polyp/adenoma detection rate (PDR/ADR), and mean number of adenomas per colonoscopy (APC) were compared in matched-control patients (n = 260) who underwent standard colonoscopy (SC). Accordingly, endoscopists subjectively evaluated the utility of FUSE colonoscopy. Results. The CIR of FUSE colonoscopy was 94.6%. Cecal intubation time (8.8 min versus 5.1 min, P < 0.001) and total procedure time (21.6 min versus 17.3 min, P < 0.001) in the FUSE group were significantly longer than those in the SC group. PDR (68.3 versus 71.2%, P = 0.567), ADR (63.4% versus 58.5%, P = 0.355), and APC (1.4 versus 1.4, P = 0.917) were not significantly different between the two groups. The wide view of FUSE colonoscopy was superior to that of SC based on the questionnaires. Conclusions. FUSE colonoscopy did not demonstrate superiority to SC in a clinical setting.

Assessment of Awareness Levels toward Colorectal Cancer Early Detection and Prevention in Saudi Arabia

“…High-quality colonoscopy is needed to reduce the morbidity and mortality of colorectal cancer. Full-spectrum endoscopy has recently shown potential in improving adenoma detection during colonoscopy [23]. Miss rate of polyps has been shown to be substantially lower with full-spectrum endoscopy (FUSE) compared with standard forward-viewing (SFV) colonoscopy in a tandem study at per polyp analysis.…”

Panoramic colonoscopy in colorectal cancer screening - a randomized controlled trial.

“…It was rated higher than SFV in only three categories: field of view, screening and polyp surveillance. In the remaining 11 categories it was rated as inferior to SFV colonoscopy [ 23 ].…”

Full‐spectrum versus standard colonoscopy for improving polyp detection rate: A systematic review and meta‐analysis

“…We excluded the following: (i) observational studies; (ii) trials not reporting any of the primary outcomes; and (iii) studies not written in English. .…”

“…In the last years, a number of randomized‐controlled trials (RCTs) and retrospective studies have explored the efficacy of FUSE as compared with standard colonoscopy (SC), providing conflicting results …”