Preliminary Exploration of Setting the Disease Severity Score in the Nutritional Risk Screening of Patients with Severe Novel Coronavirus Pneumonia by Applying NRS2002

Sun, Yucheng; He, Jing; Li, Weiming; Li, Shumin; Lin, Yueying; Cen, Yunyun; Li, Yanli

doi:10.2147/ijgm.s289655

Cited by 3 publications

(3 citation statements)

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“…The European Society for Clinical Nutrition and Metabolism (ESPEN) recommends Nutrition Risk Screening 2002 (NRS2002) as a nutritional screening tool for general inpatients ( 17 ). For hospitalized COVID-19 patients, previous literature has validated the feasibility of NRS2002 for nutritional risk screening ( 18 , 19 ). Therefore, this study aims to assess the association of nutritional risk and the NRS2002 score with the disease progression and prognosis of COVID-19 patients.…”

Section: Introductionmentioning

confidence: 99%

“…A global pandemic of coronavirus disease 2019 (COVID- 19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a serious threat to global health (1). Since the World Health Organization declared COVID-19 an epidemic on March 11, 2020 (2), the number of confirmed cases has increased daily, as many as 676,363,591 confirmed cases and 6,879,900 deaths as of March 8, 2023 (3).…”

Section: Introductionmentioning

confidence: 99%

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Nutritional risk and a high NRS2002 score are closely related to disease progression and poor prognosis in patients with COVID-19

Zhou

Chen²,

Zhang³

et al. 2023

Front. Nutr.

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BackgroundOrganism can lead to excessive nutrient consumption in the infected state and increase nutritional risk, which is detrimental to the control of the infection and can further aggravate the disease.ObjectivesTo investigate the impact of nutritional risk and the NRS2002 score on disease progression and prognosis in patients with COVID-19.MethodsThis was a retrospective cohort study including 1,228 COVID-19 patients, who were divided into a with-nutritional risk group (patients with NRS2002 score ≥ 3) and a without-nutritional risk group (patients with NRS2002 score < 3) according to the NRS2002 score at admission. The differences in clinical and outcome data between the two groups were compared, and the relationship between the NRS2002 score and the disease progression and prognosis of COVID-19 patients was assessed.ResultsOf 1,228 COVID-19 patients, including 44 critical illness patients and 1,184 non-critical illness patients, the rate of harboring nutritional risk was 7.90%. Compared with those in the without-nutritional risk group, patients in the with-nutritional risk group had a significantly longer coronavirus negative conversion time, significantly lower serum albumin (ALB), total serum protein (TP) and hemoglobin (HGB) at admission, discharge or 2 weeks, a significantly greater proportion with 3 or more comorbidities, and a significantly higher rate of critical illness and mortality (all p < 0.001). Multiple regression analysis showed that nutritional risk, NRS2002 score and ALB at admission were risk factors for disease severity. In addition, nutritional risk, NRS2002 score and TP at admission were risk factors for prognosis. The NRS2002 score showed the best utility for predicting critical illness and death in COVID-19 patients.ConclusionNutritional risk and a high NRS2002 score are closely related to disease progression and poor prognosis in COVID-19 patients. For patients with NRS2002 score > 0.5, early intervention of malnutrition is needed to reduce the occurrence of critical disease. Additionally, for patients with NRS2002 score > 5.5, continuous nutritional support therapy is needs to reduce mortality and improve prognosis.Clinical Trial registration: [https://www.chictr.org.cn/historyversionpub.aspx?regno=ChiCTR2000034563], identifier [Chinese Clinical Trial Register ChiCTR2000034563].

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Nutritional risk and a high NRS2002 score are closely related to disease progression and poor prognosis in patients with COVID-19

Zhou

Chen²,

Zhang³

et al. 2023

Front. Nutr.

View full text Add to dashboard Cite

show abstract

“…The European Society for Clinical Nutrition and Metabolism (ESPEN) recommends Nutritional Risk Screening 2002 (NRS2002) as a nutritional screening tool for general inpatients [15] . For hospitalized COVID-19 patients, literatures have validated the feasibility of NRS2002 for nutritional risk screening [16,17] . This study aims to assess the association of having nutritional risk and NRS2002 score with the disease progression and prognosis of COVID-19 patients.…”

Section: Introductionmentioning

confidence: 99%

The relationship of nutritional risk and NRS2002 score with disease progression and prognosis in patients with COVID-19

Zhou

Chen

Zhao

et al. 2022

Preprint

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Objectives: To investigate the relationship between nutritional risk and Nutritional Risk Screening 2002 (NRS2002) score with disease progression and prognosis in patients with COVID-19. Methods: The NRS2002 score of 1228 COVID-19 patients were retrospective analyzed, they were divided into with-nutritional risk group (NRS2002 score≥3) and without-nutritional risk group (NRS2002 score<3) according to the NRS2002 score at admission. To compare the differences between the two groups in clinical and outcome data and assess the relationship between the NRS2002 score and the disease progression and prognosis of COVID-19 patients. Results: Of 1228 COVID-19 patients, the nutritional risk rate was 7.90%. Compared with those in without-nutritional risk group, patients in with-nutritional risk group had significantly longer the coronavirus negative conversion time, obviously lower albumin (ALB), total protein (TP) and hemoglobin (HGB), obviously greater proportion with 3 or more comorbidities, and significantly higher rate of critical illness and mortality (P<0.01). Regression analysis showed that with nutritional risk, NRS2002 score and ALB were the risk factors for disease severity, and with nutritional risk, NRS2002 score and TP were the risk factors for prognosis. The NRS2002 score showed the best utility for predicting critical and dead COVID-19 patients. Conclusions: With nutritional risk and high NRS2002 score are closely related to disease progression and poor prognosis in COVID-19 patients. For patients with NRS2002 score >0.5, early intervention of malnutrition is needed to reduce the occurrence of critical disease. And for patients with NRS2002 score >5.5, continuous nutritional support therapy is needs to reduce mortality and improve prognosis. Clinical Trial Registry: Chinese Clinical Trial Register ChiCTR2000034563

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A Novel Facet of In-Hospital Food Consumption Associated with Hospital Mortality in Patients with Scheduled Admission—Addition of a Study Protocol to Test the Existence of Effects of COVID-19 in the Same Study in the Post-COVID-19 Period

Miyata,

Tsunou,

Hokotachi

et al. 2024

Nutrients

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Background: Humankind has faced unexperienced pandemic events since 2020. Since the COVID-19 pandemic has calmed down, we felt the need to verify whether in-hospital mortality had worsened compared to pre-pandemic conditions due to the COVID-19 pandemic. Objective: To test the hypothesis that daily food consumption is associated with in-hospital mortality during hospitalization and to provide baseline data to examine whether the effects of COVID-19 exist or not in post-pandemic period. Methods: All hospitalized patients staying in a single institution on the third Thursday of May, August, November, and the following February were included. Compared data: (1) among four seasons, (2) between age < 75 vs. ≥75 years, (3) between <75% vs. ≥75% of in-hospital food, and (4) logistic regression analysis to identify factors associated with in-hospital mortality. Results: In 365 inpatients, the following results were obtained: (1) no seasonality or age effect in in-hospital mortality, (2) the novel cutoff value of 75% of the hospital food requirement was used to identify poor in-hospital survivors, (3) logistic regression analysis showed low food consumption, with <75% of the hospital food requirement as the predictor of high in-hospital mortality. Conclusions: A small eater of in-hospital food < 75% during hospitalization was associated with significantly higher in-hospital mortality in patients with scheduled hospitalization in the pre-pandemic period. Then, a study protocol is proposed to test the existence of the effects of COVID-19 in the same study in the post-COVID-19 period. This study protocol is, to our knowledge, the first proposal to test the effects of food consumption in the post-COVID-19 period on in-hospital mortality in the clinical nutritional areas.

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Preliminary Exploration of Setting the Disease Severity Score in the Nutritional Risk Screening of Patients with Severe Novel Coronavirus Pneumonia by Applying NRS2002

Cited by 3 publications

References 13 publications

Nutritional risk and a high NRS2002 score are closely related to disease progression and poor prognosis in patients with COVID-19

Nutritional risk and a high NRS2002 score are closely related to disease progression and poor prognosis in patients with COVID-19

The relationship of nutritional risk and NRS2002 score with disease progression and prognosis in patients with COVID-19

A Novel Facet of In-Hospital Food Consumption Associated with Hospital Mortality in Patients with Scheduled Admission—Addition of a Study Protocol to Test the Existence of Effects of COVID-19 in the Same Study in the Post-COVID-19 Period

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