2023
DOI: 10.1186/s12957-023-03106-6
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Preliminary exploration of the effects of environmental factors on the microsatellite status of BRAF-mutated colorectal cancer

Binle Tian,
Guiming Chen,
Xiaoqin Shi
et al.

Abstract: Background To investigate the expression of EBV products and frequency of gallstone disease (GD) among different microsatellite status in colorectal cancer (CRC) with BRAFV600E mutation. Methods We collected 30 CRC patients with BRAFV600E mutation and 10 BRAF ( −) CRC patients as well as 54 healthy subjects. Tumor tissue samples were collected to detect the mutation of BRAF, KRAS, and TP53. Microsatellite status was determined by immunohistochemist… Show more

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