Preliminary Observations on the Prenatal Administration of Demethylchlortetracycline HCI

Abstract

Prenatal administration of tetracycline has previously been reported to cause staining of the infants' teeth. Demethylchlortetracycline has not previously been implicated. Five cases are presented in which demethylchlortetracycline was administered prenatally. In each case, there was staining of those teeth that were undergoing mineralization at the time the drug was administered.