Preliminary Phytochemical Screening of Diospyros Mespiliformis

Aa, Ebbo; Mammam,; Сулейман, М. М.; Ahmed, C. M. Sabbir; Bello, A.

doi:10.4172/2161-0940.1000156

Cited by 5 publications

(2 citation statements)

References 9 publications

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“…Seed extracts inhibited hydrophila, which is already proven to be multidrug resistant. These findings are important since A. hydrophila is capable of producing a variety of enterotoxins that can result in dysenteric gastroenteritis [21]. The fungal strains exhibited a higher sensitivity to the seed extract based on ethanol and methanol compared to the chloroform and water extracts [21].…”

Section: Discussionmentioning

confidence: 99%

“…These findings are important since A. hydrophila is capable of producing a variety of enterotoxins that can result in dysenteric gastroenteritis [21]. The fungal strains exhibited a higher sensitivity to the seed extract based on ethanol and methanol compared to the chloroform and water extracts [21]. Similarly, the effects of papaya on seed germination and seedling emergence of African yam bean (Sphenostylis stenocarpa) was appraised after exposing them to seed-borne fungi, A. niger, A. flavus, B. theobromae, and F. moniliforme [22].…”

Section: Discussionmentioning

confidence: 99%

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In Vitro Evaluation of Antimicrobial and Antioxidant Activity of Carica Papaya L. Seeds Grown in the Republic of Yemen

Al-Hajj

2021

Electron. J. Univ. Aden Basic Appl. Sci.

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This study aimed to investigate the phytochemical, antimicrobial, and antioxidant activities of Carica papaya L. seeds extracts collected from Al Hudaydah city, Yemen (Latitude: 14°47′52″ N Longitude: 42°57′16″ E) during the months of January and February 2021. The seed was extracted with different solvents by the cold percolation method. The disk diffusion method was employed to assess the antibacterial activity of the seed extract against six bacterial and four fungal strains. Spectrometric methods were employed to calculate the total alkaloids, anthocyanin, flavonoid, phenolic, quinones, saponin, steroids, terpenoid, tannin, and phenols contents, as well as the antioxidant activities. Antibacterial and antifungal activity tests exhibited that the selected microorganisms are highly sensitive to the ethanolic and methanolic extracts of C. papaya L. seeds, followed by chloroform, water, and n-hexane extracts. The samples also demonstrated a significant DPPH, FRAP, and APTS radical scavenging activity. Additionally, the preliminary phytochemical analysis revealed the presence of flavonoid, terpenoid, saponin, alkaloids, steroids, quinones, anthocyanin, tannin, and phenols, all of which potentially contribute to the antimicrobial activities of C. papaya L. seeds.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

In Vitro Evaluation of Antimicrobial and Antioxidant Activity of Carica Papaya L. Seeds Grown in the Republic of Yemen

Al-Hajj

2021

Electron. J. Univ. Aden Basic Appl. Sci.

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Biogenic Synthesis of Selenium Nanoparticles using Diospyros montana Bark Extract: Characterization, Antioxidant, Antibacterial, and Antiproliferative Activity

Puri¹,

Patil²

2022

Biosci., Biotech. Res. Asia

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Selenium nanomaterials (Nano-Se) are new selenium sources with excellent biocompatibility, degradability, and bioactivities. The objective of the present study is the green synthesis of selenium nanoparticles (SeNPs) using Diospyros montana Roxb (DM) bark extract, its characterization, and evaluation for in-vitro antioxidant, antibacterial and anticancer activities. To synthesize Diospyros montana- selenium nanoparticles (DM-SeNPs), selenious acid (H2SeO3) was reduced using D. montana extract via precipitation technique. UV-Vis, FTIR, XRD, SEM, EDAX, and ICP-AES were used to characterize DM-SeNPs. The DPPH free radical scavenging assay and reducing power capacity were used to test DM-SeNP for antioxidant activity. The antibacterial properties of the DM-SeNP were tested using the well diffusion method against gram-positive and gram-negative microorganisms. DM-SeNPs were also subjected to antiproliferative activity using MTT assay via MCF-7 cell line. A peak in UV at 289 nm validated the synthesis of DM-SeNPs. According to DLS, SEM, and TEM images, the size of DM-SeNPs was between 100-150 nm. XRD analysis confirmed the crystallinity of DM-SeNPs. Selenium was verified in colloidal dispersion using EDAX analysis, and ICP-AES confirmed selenium content 63.45 ±18.3 µg/mL in DM-SeNP. The IC50 24.72 ± 0.63 µg/mL and EC50 46.30 ± 0.21 µg/mL values indicated that the DM-SeNPs had a good antioxidant capacity. DM-SeNPs showed comparative better antibacterial potential. The inhibition zones were found to be the highest for E. coli (48.00 mm), B. subtilis (44.14 mm), Klebsiella pneumonia (36.20 mm), and S. aureus (34.16mm), respectively. Antiproliferative activity was carried out, which showed DM-SeNPs were cytotoxic to breast cancer cells line (MCF-7). The IC50 values for DM-SeNPs were found to be 38.19 ± 0.27 µg/mL and Doxorubicin 6.41 ± 0.09 µg/mL, respectively. The study suggests that DM-SeNPs display moderate cytotoxicity that could dose-dependently inhibit cell proliferation. Thus, experimental evidence provides insight into selenium nanoparticle synthesis, its potential therapeutic value, and the prospect of developing a formulation containing DM-SeNPs.

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Brief Review of the Genus Diospyros Montana Roxb: Phytopharmacological Properties

Sujatha

Arul

2022

Extsv. Rev.

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Diospyros montana Roxb. (F: Ebenaceae) commonly known as Ebony is a species of flowering tree native to India and other countries. These plant part as a whole in used in treatment of several diseases in particular, leaves and bark are used in folk medicine for the treatment of fish poison, anti-inflammatory, anti cancer etc. This present investigation reviews the bioactivity of flavonoids, phenols, carbohydrates, amino acids, protein, saponins, alkaloids, tannins, sterols, anthocyanin and anthraquinones, fixed oils and fats, and their presence in various parts of Diospyros montana. The significant constituent such as Diospyros, Isodiospyrin, Oleanolic acid, quercetin, β-amyrin and kaempferol have been isolated from various parts of the plant is discussed with a detailed description. The narrower approach indicates that Diospyros montana possess various pharmacological activities like antiviral, anticancer, antitumor, antimalarial, anthelmintic, prostaglandin synthesis inhibitory, anti-inflammatory, hypolipidemic, and antileukemic agent and several other important medicinal properties. This review focus on comprehensive and categorized information on the botany, traditional uses, phytochemistry and pharmacological aspects of Diospyros montana which provide valuable information to researchers for continuing further scientific work on this plant.

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Preliminary Phytochemical Screening of Diospyros Mespiliformis

Cited by 5 publications

References 9 publications

In Vitro Evaluation of Antimicrobial and Antioxidant Activity of Carica Papaya L. Seeds Grown in the Republic of Yemen

In Vitro Evaluation of Antimicrobial and Antioxidant Activity of Carica Papaya L. Seeds Grown in the Republic of Yemen

Biogenic Synthesis of Selenium Nanoparticles using Diospyros montana Bark Extract: Characterization, Antioxidant, Antibacterial, and Antiproliferative Activity

Brief Review of the Genus Diospyros Montana Roxb: Phytopharmacological Properties

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