Preliminary Results With Combined Hepatorenal Allografting

Vogel, Wolfgang; Steiner, E; Kornberger, R; Koller, Johann; Spielberger, M; Aulitzky, Walter; Huber, Christoph; Judmaier, G; Margreiter, Raimund

doi:10.1097/00007890-198802000-00050

Cited by 32 publications

(8 citation statements)

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“…It has been hypothesized that maintaining a proper concentration of soluble HLA in circulation would lead to tolerance to the allotype of the soluble HLA. This concept may help explain the protection of a simultaneous kidney and heart transplant by a successful human liver transplant (20). Therefore, less intensive immunosuppression therapy for these patients after CHLTx than for IHTx may be justified.…”

Section: Discussionmentioning

confidence: 99%

Combined Heart and Liver Transplantation: A Single-Center Experience

et al. 2009

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Section: Discussionmentioning

confidence: 99%

Combined Heart and Liver Transplantation: A Single-Center Experience

et al. 2009

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“…Early acute kidney rejection rates in combined transplantation are on average less than 10% (Table 10). 12,42,43,[46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61]65,80 This is compared with rejection rates of 30% to 50% reported in the literature for temporally matched kidney-only transplant recipients. 65 Thus, even with less HLA matching and a positive cross-match, renal rejection rates appear to be lower when a liver allograft is placed concurrently ( 3).…”

Section: Allograft Rejection After Lktmentioning

confidence: 99%

Identification of patients best suited for combined liver[ndash ]kidney transplantation: Part II

Davis

Gonwa

Wilkinson

2002

Liver Transplantation

117

105

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Liver-kidney transplantation (LKT) should be reserved for those recipients with primary disease affecting both organs. However, increasing transplant list waiting times have increased the development and duration of acute renal failure before liver transplantation. Furthermore, the need for posttransplant calcineurin inhibitors can render healing from acute renal failure difficult. Because of the increasing requests for and controversy over the topic of a kidney with a liver transplant (OLT) when complete failure of the kidney is not known, the following article will review the impact of renal failure on liver transplant outcome, treatment of peri-OLT renal failure, rejection rates after LKT, survival after LKT, and information on renal histology and progression of disease into the beginnings of an algorithm for making a decision about combined LKT. (Liver Transpl 2002;8:193-211.)

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“…It has been hypothesized that maintaining a concentration of soluble HLA in the circulation would lead to tolerance to the allotype of the soluble HLA. This concept may help explain the protection of a simultaneous heart transplant by a successful human liver transplant (Vogel et al, 1988). Therefore, less intensive immunosuppression therapy for these patients after CHLTx than for IHTx may be justified.…”

Section: Acute Cellular Rejectionmentioning

confidence: 99%