Preliminary safety estimate of cosmetic anti-age creams with chokeberry extract, using in vivo bioengineering techniques

Abstract

Potential of anti-age cosmetic line, day and night creams were evaluated using noninvasive measurements of the appropriate skin biophysical parameters in a 24-h in vivo study under occlusion. Thirtyone healthy female volunteers were involved in the study. Electrical capacitance (EC), transepidermal water loss (TEWL), erythema index (EI) were evaluated. The preliminary safety profile of the investigated creams with natural origin ingredients based on obtained results can be considered satisfactory. The stated samples did not cause the change in the measured biophysical parameters-TEWL and EI, while they increased EC i.e. stratum corneum hydration. These results suggest that chokeberry extract and other natural ingredients could exert beneficial effects and has potential on aged skin thereby slowing down the appearance of wrinkles and their existing alleviation, and they could be considered preferable in the cosmetic products intended for the treatment of aged skin.

The impact of puffball autolysis on selected chemical and biological properties: Puffball extracts as potential ingredients of skin-care products

“…Phenolic acids were not detected in L. perlatum either, while only traces ofp-hydroxybenzoic and vanillic acid were found in L. molle (41.66 and 39.99 mg/kg dry mass, respectively) [22]. Phenolic compounds and antioxidants in general have been shown to have beneficial effects on the skin, especially in preventing premature skin aging and wrinkling [23].…”

“…In general, the process of autolysis in puffballs leads to the production and/or improved availability of certain compounds that may benefit skin health (N-acetylglucosamine, α-tocopherol, ergosterol, linoleic acid and phenolics), and many of them are probably involved in skin regeneration [23,[26][27][28]. However, the extraction processes need to be optimized as these compounds have different hydrophilic/hydrophobic characteristics.…”

Biocosmetics: technological advances and future outlook

“…Jerusalem artichoke extract or powder fermented with P. rhodozyma for astaxanthin synthesis was studied because of its anti-inflammatory, sun proofing, antiaging, antioxidative, and immune-boosting functions (Jiang et al 2017). Aronia melanocarpa leaf and fruit extract are used in cosmetic products for skin conditioning, skin whitening, anti-inflammatory, and collagen-boosting properties (Cujic et al 2017;Lee and Ryu 2018). Novel cosmeceutical delivery systems that act as smart carriers for encapsulation or attachment of therapeutic ingredients need to be explored.…”