Preliminary Study of Newborn Screening for Congenital Hypothyroidism and Congenital Adrenal Hyperplasia in Indonesia

Pulungan, Aman B; Soesanti, Frida; Utari, Agustini; Pritayati, Niken; Julia, Madarina; Annisa, Diadra; Andarie, Attika Adrianti; Bikin, I Wayan

doi:10.23886/ejki.8.11611.

Cited by 8 publications

(14 citation statements)

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“…According to Deliana et al (2016), cases of congenital hypothyroidism in Indonesia occur sporadically with an estimated prevalence of 1:2916. However, a recent study carried out in 2020 displayed a higher prevalence of 1:1167 (Pulungan et al, 2020).…”

Section: Introductionmentioning

confidence: 85%

The Evaluation of Congenital Hypothyroidsm Screening Program in Indonesia: A Literature Review

Setyaningsih

Wulandari

2022

J. Sci. n.a

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Congenital hypothyroidism is one of the main causes of mental retardation which can be prevented. Reasearch in 2020 found that the prevalence of congenital hypothyroidism in Indonesia was 1:1167. During the previous 18 years of impelementation of the Congenital Hypothyroidsm Screening Program (CHSP), it was found that only 4,6% of newborns. This study aims to conduct a literature review to identify problems and obtain information on improving the implementation of congenital hypothyroidism screening programs in Indonesia. This research was carried out between November-December 2021 and consists of a review of a range of research articles and journals which have been publishes within the last decade. Several studies have shown that during the implementation of the CHSP, several onstacles were found which hindered the effectiveness of the program, namely the lack of training for health workers, sources of financing which have not been fully borne by the center, accuracy of collection and sample delivery, and less than optimal management function in regulating the implementation of the program thus a more in-depth evaluation needed, especially in terms of economic benefits and the level of effectiveness of the screening program.

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Section: Introductionmentioning

confidence: 85%

The Evaluation of Congenital Hypothyroidsm Screening Program in Indonesia: A Literature Review

Setyaningsih

Wulandari

2022

J. Sci. n.a

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“…Data obtained from the results of the "1000 Congenital Hypothyroid Screening Babies" program conducted at the Perinatology section of the Department of Pediatrics, RSCM, found 4 babies with congenital hypothyroidism detected from 1000 babies examined. 5 Based on the results of the 2018 Basic Health Research report, it was found that the proportion of CHS examinations was still very low, which was only 4.6% for the total proportion of CHS in Indonesia. The data showed that DI Yogyakarta Province is the area with the highest proportion of CHS examinations, as many as 14.6%, and the lowest is North Sumatra Province with the proportion of CHS examinations being only 1.7%.…”

Section: Original Articlementioning

confidence: 99%

“…The incidence rate could be compared with others, such as research by Pulungan et al, there was 1 case out of 1226 subjects. 5 Researches in Sri Lanka (1:1682), India (1:6813), Laos (1:5861), Saudi Arabia (1:7175). 13,16…”

Section: Original Articlementioning

confidence: 99%

Screening for congenital hypothyroidism in Malang, East Java in 2020

Salim

Putri

Rosmalawati

et al. 2022

PEDSCIJ

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Introduction: Congenital hypothyroidism is defined as a state of thyroid hormone deficiency present at birth. Congenital hypothyroidism must be diagnosed immediately because delay in therapy may cause irreversible neurological deficits, such as mental retardation in children. However, this condition can be prevented by screening in newborns so that congenital hypothyroidism can be diagnosed and treated early, and can result in better neurological development. This study aims to determine the congenital hypothyroidism ratio in Malang from March to November 2020. Methods: The descriptive analysis method was used in this research. The subjects were neonates aged 0 – 28 days with a gestational age of 36 weeks and were involving the Health Office in both the Regency and the City of Malang. The data about identity, gender, age at screening, and gestational age were collected. A laboratory screening test was performed by taking a blood sample from the heel or vein for a TSH test. If the result was positive with a TSH value > 20 U/mL, the subject would be recalled for having a confirmation test and referred to a pediatric endocrinologist. Results: There were 2024 (88.34%) subjects were successfully screened from a total of 2291 subjects. The recall rate for congenital hypothyroidism was 1:2024 (0.04%). Conclusion: The ratio of congenital hypothyroidism cases in Malang from March to November 2020 was higher than the global ratio, which was 1:3000. The high rate of congenital hypothyroidism in Malang indicated the need for congenital hypothyroidism screening in newborns.

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“…1,2 Angka kejadian HK di dunia adalah 1 dari 2000-4000 bayi, lebih sering pada perempuan. 1,3 Kejadian HK pada populasi Asia dilaporkan lebih tinggi dibandingkan populasi Barat. 4 Di Indonesia, belum ada data nasional angka kejadian HK.…”

Section: Pendahuluanunclassified

“…Cakupan deteksi dini HK di Indonesia masih kurang dari 2% dan hanya terpusat di kota besar seperti Jakarta. 3 Saat munculnya gejala HK bergantung pada keparahan defisiensi hormon tiroksin. Pada defisiensi hormon berat (misal, akibat agenesis kelenjar tiroid), gejala dapat muncul pada awal kehidupan.…”

Section: Pendahuluanunclassified

Hipotiroid Kongenital dan Hypertrophic Pyloric Stenosis: Pemantauan Selama 3 Bulan

Gultom

The

2022

CDK

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Angka kejadian hipotiroid kongenital (HK) berkisar 1 : 2000-4000 bayi. Deteksi dan tata laksana dini diperlukan agar fungsi neurologi dan perkembangan pasien optimal. Salah satu penyebab muntah berulang pada bayi adalah hypertrophic pyloric stenosis (HPS). Deteksi dan tata laksana HPS penting karena HPS dapat menyebabkan gagal tumbuh hingga gizi buruk yang berdampak pada IQ. Kasus: Bayi usia 2 bulan tanpa skrining hipotiroid kongenital, masuk ke rumah sakit dengan gejala khas hipotiroid kongenital, yaitu ubun-ubun terbuka, wajah tampak kasar, makroglosia, kulit kering dan dingin, gagal tumbuh, dan hernia umbilikalis. Selain gejala HK, bayi juga memiliki keluhan muntah berulang yang kemudian didiagnosis HPS. Terapi medikamentosa yang tepat dengan levothyroxine, tindakan pembedahan, dan nutrisi yang adekuat harus diberikan agar tumbuh kembang optimal.

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Preliminary Study of Newborn Screening for Congenital Hypothyroidism and Congenital Adrenal Hyperplasia in Indonesia

Cited by 8 publications

References 0 publications

The Evaluation of Congenital Hypothyroidsm Screening Program in Indonesia: A Literature Review

The Evaluation of Congenital Hypothyroidsm Screening Program in Indonesia: A Literature Review

Screening for congenital hypothyroidism in Malang, East Java in 2020

Hipotiroid Kongenital dan Hypertrophic Pyloric Stenosis: Pemantauan Selama 3 Bulan

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