Preliminary study on the development of an antistretch marks water-in-oil cream: ultrasound assessment, texture analysis, and sensory analysis

Abstract

PurposeStriae distensae represent the result of the failure of the dermis to sustain intrinsic mechanical forces. Intensive moisturization of the lesions and use of emollient oils have been recommended for the prevention and treatment of striae distensae rubra. The aim of this research was to formulate an emollient water-in-oil cosmetic cream containing argan oil, which may be helpful in the prevention or early treatment of striae distensae.Patients and methodsSensory evaluation of the consistency, firmness, adhesiveness, oiliness, spreadability, and rapidity of penetration into the skin was evaluated by 22 volunteers using 10-point scales for each descriptor. The instrumental characterization of the cream was performed using Brookfield® CT3 Texture Analyzer. The cutaneous changes induced by the topical use of the cream were evaluated by assessing the thickness of the epidermis, hydration, and elasticity of the skin using DermaLab® Combo scanner.ResultsUltrasound measurements showed an improvement in the elasticity of the epidermis following the application of cream. The product was well tolerated and appreciated by the consumers in terms of its spreadability, penetration ability, and lack of stickiness. The values recorded for texture analysis were firmness 10.16±0.15 mJ, adhesiveness 30.94±6.87 g, consistency 1229.50±119.78 g, spreadability 481.50±39 g, and stringiness 0.56±0.09 mJ.ConclusionA water-in-oil cream containing argan oil and emollient ingredients with appropriate physical characteristics was obtained. In vivo study of clinical efficacy revealed a positive effect on increasing the skin elasticity, suggesting that the cream may be helpful in the prevention or early treatment of striae distensae.

Formulation and Physicochemical Evaluation of a Herbal Dentifrice Formulated with Myristica fragrans (Nutmeg): An In Vitro Study

“…(16) This is important to consider in the deciduous dentition since the tooth enamel is thinner and can increase the risk of caries progression in these teeth. (11) In the present study, the formulated nutmeg toothpaste has lesser abrasivity than the standard, which could be advantageous for children with mixed dentition owing to the thickness of enamel.…”

“…The hardness of both toothpastes was recorded from the graph obtained, which is inversely proportional to their spreadability. (11)…”

Treatment of Stretch Marks Using a New Formulation Combining Nanofractional Radiofrequency Plus Magnetic Nanofractional Radiofrequency

“…Skin elasticity was evaluated using the Cutometer MPA580, which assesses the viscoelastic properties of human skin through the suction approach [ 39 ]. Skin thickness and collagen density were measured using the DermLab Combo [ 40 ]. Skin color was evaluated using the CM2600d with L*a*b* measurements [ 41 ].…”