Preliminary Study on the In vitro and In vivo Effects of Asparagopsis taxiformis Bioactive Phycoderivates on Teleosts

Abstract

Several compounds from marine organisms have been studied for their potential use in aquaculture. Among the red algae, Asparagopsis taxiformis is considered one of the most promising species for the production of bioactive metabolites with numerous proposed applications. Here, the in vitro antibacterial activity, the easy handling and the absence of adverse effects on marine fish species are reported. Depending on the seasonal period of sampling, ethanol extracts of A. taxiformis exhibited significantly different inhibitory activity against fish pathogenic bacteria. The extract obtained in late spring showed strong antibacterial activity against Aeromonas salmonicida subsp. salmonicida, Vibrio alginolyticus, and V. vulnificus, and moderate activity against Photobacterium damselae subsp. damselae, P. damselae subsp. piscicida, V. harveyi and V. parahaemolyticus. Sea bass and gilthead sea bream were fed with pellets supplied with the alga and algal extracts. The absence of undesired effects on fish was demonstrated. Hematological and biochemical investigations allowed to confirm that the whole alga and its extracts could be proposed for a future application in aquaculture.

Effects of dietary supplementation with a microalga (Schizochytrium sp.) on the hemato-immunological, and intestinal histological parameters and gut microbiota of Nile tilapia in net cages

“…In a study evaluating the effect of the alga Sargassum ilicifolium in the diet of a sturgeon (Huso huso), it was found that supplying algae at the concentration of 10% of the diet increased the number of WBCs, with an increase in the numbers of neutrophils and a decrease in the number of lymphocytes [46]. In sea bream (Sabanejewia aurata) fed with the alga Asparagopsis taxiformis and its extract, significant decreases (p < 0.05) in RBC counts, Hb, Ht, and WBC counts were found [47]. That study's authors suggested that the inclusion of algae in the diet had negative effects on hematological parameters, which could be related to a dose/response effect.…”

Antioxidant and cytotoxic activities of sulfated polysaccharides from five different edible seaweeds

“…The antioxidant and in vitro cytotoxic activity of extracts prepared using methanol, chloroform, petroleum ether and ethyl acetate from red alga Asparagopsis taxiformis were demonstrated [ 13 ]. In another study, ethanol extract significantly exhibiting antibacterial activity against fish pathogenic bacteria was found [ 14 ]. Ethanolic extract of brown alga, Padina pavonica having antimicrobial, antioxidant, and anticancer activities was proved [ 15 ].…”

Effect of Dietary Vitamin C Supplementation on the Blood Parameters of Striped Bass Morone saxatilis (Walbaum, 1752)

“…Today, fish nutrition and its effect to animal health is an important new field of study in the aquaculture industry (Lo Cascio et al, 2018;Marino et al, 2016).…”