Premature birth, infections, and atherosclerotic cardiovascular disease

Mehta, J. L.; Bavineni, Mahesh

doi:10.1093/eurheartj/ehz441

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…Some premature babies have a good prognosis after positive treatment, while some others have adverse outcomes due to various diseases or improper nursing, which is an important factor causing premature infant death [ 3 ]. According to statistics, the global mortality rate of PTIs has reached 20.8%, showing an increasing trend [ 4 ]. PTIs with very low birthweight have an increased risk of abnormal lung function, particularly obstructive type and thoracic musculoskeletal abnormalities, which were related with alternations in lung function [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Impact of Kangaroo Mother Care Intervention on Immunological and Pulmonary Functions of Preterm Infants during Breastfeeding

Yang¹,

Guo

Dai

2022

Evidence-Based Complementary and Alternative Medicine

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Objective. Preterm infants (PTIs) are prone to respiratory failure or other diseases due to immature organ development and poor immunological function. Herein, the effects of Kangaroo Mother Care (KMC) on the immunological and pulmonary functions of PTIs during breastfeeding were investigated in this study. Methods. The study recruited 86 delivery women and their PTIs with preterm pregnancy outcomes, consisting of 46 cases receiving breastfeeding plus KMC intervention (KMC group) and 40 cases receiving breastfeeding plus routine care (control group). The time of first lactation, time of first breastfeeding, and duration of first breastfeeding were observed in both cohorts. The breastfeeding status was assessed using the LATCH system. Maternal psychological status was evaluated by the breastfeeding self-efficacy scale (BSES) and self-rating anxiety/depression scale (SAS/SDS). The growth and development of PTIs were recorded, and the levels of postalbumin (PA), transferrin (TRF), plasma albumin (ALB), immunoglobulin (Ig) A, IgG, IgM, and complement C3 and C4 were measured. The tidal volume (VT), tidal volume per kilogram (VT/kg), minute volume (MV), and minute volume per kilogram (MV/kg) were detected using a pulmonary function tester. Results. The KMC group presented shorter time of first lactation and first breastfeeding than the control group, with longer duration of first breastfeeding ( P < 0.05 ). After intervention, the BSES scores of delivery women were increased, while the SAS and SDS scores were decreased, with more notable improvements in the KMC group ( P < 0.05 ). The levels of PA, TRF, ALB, IgA, IgG, VT, and MV were elevated in PTIs in both groups, with more evident increase in the KMC group than in the control group ( P < 0.05 ). A better growth of PTIs was found in the KMC group than the control group ( P < 0.05 ). Conclusions. The study demonstrated that KMC intervention during breastfeeding could benefit PTIs specifically regarding their immunological and pulmonary functions.

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Section: Introductionmentioning

confidence: 99%

Impact of Kangaroo Mother Care Intervention on Immunological and Pulmonary Functions of Preterm Infants during Breastfeeding

Yang¹,

Guo

Dai

2022

Evidence-Based Complementary and Alternative Medicine

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“…Longitudinal studies have shown that individuals who were born prematurely have endothelial dysfunction as children that persists into young adulthood and a greater risk of cardiovascular disease in adulthood. 58 , 59 These children have greater risk of infections in infancy and childhood, 60 and this increase in infection exposure has been tied to later cardiovascular disease. 61 Similarly, exposure to secondhand smoke in childhood is associated with increased risk of carotid plaque in adulthood.…”

Section: Post Covid-19 Condition and Endothelial Epigeneticsmentioning

confidence: 99%

Acute and Chronic Cardiovascular Manifestations of COVID-19: Role for Endotheliopathy

Cooke

Connor

Jain

2021

Methodist DeBakey Cardiovascular Journal

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SARS-CoV-2, the virus that causes coronavirus disease 19 (COVID-19), is associated with a bewildering array of cardiovascular manifestations, including myocardial infarction and stroke, myocarditis and heart failure, atrial and ventricular arrhythmias, venous thromboembolism, and microvascular disease. Accumulating evidence indicates that a profound disturbance of endothelial homeostasis contributes to these conditions. Furthermore, the pulmonary infiltration and edema, and later pulmonary fibrosis, in patients with COVID-19 is promoted by endothelial alterations including the expression of endothelial adhesion molecules and chemokines, increased intercellular permeability, and endothelial-to-mesenchyme transitions. The cognitive disturbance occurring in this disease may also be due in part to an impairment of the blood-brain barrier. Venous thrombosis and pulmonary thromboembolism are most likely associated with an endothelial defect caused by circulating inflammatory cytokines and/or direct endothelial invasion by the virus. Endothelial-targeted therapies such as statins, nitric oxide donors, and antioxidants may be useful therapeutic adjuncts in COVID-19 by restoring endothelial homeostasis.

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Endocarditis: the Cinderella of Cardiology is back!

Lüscher

2019

European Heart Journal

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Premature birth, infections, and atherosclerotic cardiovascular disease

Cited by 3 publications

References 4 publications

Impact of Kangaroo Mother Care Intervention on Immunological and Pulmonary Functions of Preterm Infants during Breastfeeding

Impact of Kangaroo Mother Care Intervention on Immunological and Pulmonary Functions of Preterm Infants during Breastfeeding

Acute and Chronic Cardiovascular Manifestations of COVID-19: Role for Endotheliopathy

Endocarditis: the Cinderella of Cardiology is back!

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