Premature coronary heart disease: the influence of positive family history on platelet activity in vivo in children and adolescents (family study)

Platelet hyperactivity in clinical depression and the beneficial effect of antidepressant drug treatment: how strong is the evidence?

“…The focus was put on studies providing data on changes in platelet activity markers (36) commonly believed to be associated with CAD (55–58). Those were (i) platelet aggregability in response to specific platelet receptor agonists like ADP, epinephrine (EPI), or serotonin (ST); (ii) the platelet releasing factors PF4 and β TG in plasma; (iii) expression levels of a variety of platelet surface GP such as GPIb and GPIIb/IIIa, and (iv), expression of platelet activation markers on the surface such as activated GP IIb/IIIa and P‐selectin (P‐selectin).…”