PURPOSE Self-harm is a public health problem that requires a better understanding of mortality risk. We undertook a study to examine premature mortality in a nationally representative cohort of primary care patients who had harmed themselves. During 2001During -2013, a total of 385 general practices in England contributed data to the Clinical Practice Research Datalink with linkage to Office for National Statistics mortality records. We identified 30,017 persons aged 15 to 64 years with a recorded episode of self-harm. We estimated the relative risks of all-cause and cause-specific natural and unnatural mortality using a comparison cohort of 600,258 individuals matched on age, sex, and general practice.
METHODS
RESULTSWe found an elevated risk of dying prematurely from any cause among the self-harm cohort, especially in the first year of follow-up (adjusted hazard ratio for that year, 3.6; 95% CI, 3.1-4.2). In particular, suicide risk was especially high during the first year (adjusted hazard ratio, 54.4; 95% CI, 34.3-86.3); although it declined sharply, it remained much higher than that in the comparison cohort. Large elevations of risk throughout the follow-up period were also observed for accidental, alcohol-related, and drug poisoning deaths. At 10 years of follow-up, cumulative incidence values were 6.5% (95% CI, 6.0%-7.1%) for allcause mortality and 1.3% (95% CI, 1.2%-1.5%) for suicide.CONCLUSIONS Primary care patients who have harmed themselves are at greatly increased risk of dying prematurely by natural and unnatural causes, and especially within a year of a first episode. These individuals visit clinicians at a relatively high frequency, which presents a clear opportunity for preventive action. Primary care patients with myriad comorbidities, including self-harming behavior, mental disorder, addictions, and physical illnesses, will require concerted, multipronged, multidisciplinary collaborative care approaches. Ann Fam Med 2017;15:246-254. https://doi.org/10.1370/afm.2054.
INTRODUCTIONS elf-harm is a major public health problem. Deprived populations have a higher incidence of self-harm, 1 and national incidence rates have risen in the wake of the economic downturn and subsequent austerity era.2 A greatly reduced life expectancy and an elevated risk of early death have been reported among people who seek care at hospitals after self-harm in Australia, 3 (Self-Harm: Longer-Term Management, 2011), and was Chair of the NICE Self-harm, Quality Standard Topic Expert Group (2013) For the study reported here, we used electronic health data linked to national mortality records to investigate the risk of dying prematurely after selfharm in a large primary care cohort in England. By examining deaths from both unnatural and natural causes, our intention was to highlight the potential clinical and public health benefits of addressing the physical health as well as the psychosocial needs of these patients. We currently know very little about long-term mortality risk in this population because researcher...