Premature Ejaculation Symptoms Are Associated with Sexual Excitability: Empirical Support for the Hyperarousability Model

Ventus, Daniel; Jern, Patrick

doi:10.3390/sexes2030027

Cited by 8 publications

(4 citation statements)

References 30 publications

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“…Both structural and functional damage to thalamus highlighted a deficiency in its ejaculatory inhibition control (M. Gao et al., 2022; S. Gao et al., 2023). The higher propensity for sexual excitation and stronger reaction to sexual stimuli were found in PE patients (Ventus & Jern, 2021). Therefore, we also speculated subsequently elevated sexual inhibitory demand in the mechanism of rapid ejaculation, which is presented by enhanced nodal topological properties.…”

Section: Discussionmentioning

confidence: 98%

Topological differences of striato‐thalamo‐cortical circuit in functional brain network between premature ejaculation patients with and without depression

Zhang,

Niu,

et al. 2024

Brain and Behavior

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IntroductionPremature ejaculation (PE), a common male sexual dysfunction, often accompanies by abnormal psychological factors, such as depression. Recent neuroimaging studies have revealed structural and functional brain abnormalities in PE patients. However, there is limited neurological evidence supporting the comorbidity of PE and depression. This study aimed to explore the topological changes of the functional brain networks of PE patients with depression.MethodsResting‐state functional magnetic resonance imaging (rs‐fMRI) data were acquired from 60 PE patients (30 with depression and 30 without depression) and 29 healthy controls (HCs). Functional brain networks were constructed for all participants based on rs‐fMRI data. The nodal parameters including nodal centrality and efficiency were calculated by the method of graph theory analysis and then compared between groups. In addition, the results were corrected for multiple comparisons by family‐wise error (FWE) (p < .05).ResultsPE patients with depression had increased degree centrality and global efficiency in the right pallidum, as well as increased degree centrality in the right thalamus when compared with HCs. PE patients without depression showed increased degree centrality in the right pallidum and thalamus, as well as increased global efficiency in the right precuneus, pallidum, and thalamus when compared with HCs. PE patients with depression demonstrated decreased degree centrality in the right pallidum and thalamus, as well as decreased global efficiency in the right precuneus, pallidum, and thalamus when compared to those without depression. All the brain regions above survived the FWE correction.ConclusionThe results suggested that increased and decreased functional connectivity, as well as the capability of global integration of information in the brain, might be related to the occurrence of PE and the comorbidity depression in PE patients, respectively. These findings provided new insights into the understanding of the pathological mechanisms underlying PE and those with depression.

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Section: Discussionmentioning

confidence: 98%

Topological differences of striato‐thalamo‐cortical circuit in functional brain network between premature ejaculation patients with and without depression

Zhang,

Niu,

et al. 2024

Brain and Behavior

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“…The 5-item diagnostic tool Checklist for Early Ejaculation Symptoms (CHEES), which was developed from three earlier ejaculation diagnostic tools and has improved validity (69), was used to measure the ejaculation control of the participants. This measure has been proven to perform well in differentiating men with and without PE in a Western population sample (AUC = 0.98) (69) and to have good internal reliability of .760 (70). It has not previously been used with Chinese samples.…”

Section: Checklist For Early Ejaculation Symptoms (Chees)mentioning

confidence: 99%

Associations between Self-Reported Anatomical Characteristics of the Penis, Age and Sexual Dysfunction in Men

Ventus¹,

Jern²,

Santtila

et al. 2023

Preprint

Self Cite

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Premature ejaculation and erectile dysfunction are common male sexual dysfunctions worldwide, causing substantial distress in men as well as their partners and decrease the quality and stability of romantic relationships. We investigated the associations between self-reported anatomical characteristics of the penis and sexual dysfunctions in an urban sample of Chinese men. We recruited 1085 Chinese urban men aged 18 to 50 (M = 31.37, SD = 5.52) to fill out an online questionnaire regarding anatomical characteristics of the penis as well as early ejaculation and erectile problems via two Chinese online survey platforms. Participants reported their age, height, weight, penile length, penile circumference, circumcision status, and foreskin characteristics as well as answered the International Index of Erectile Function-5 and Checklist for Early Ejaculation Symptoms. Both increasing penile length (M = 14.49, SD = 2.22) and girth (M =15.46, SD = 4.36) were associated with fewer early ejaculation problems, but only increasing penile length was associated with fewer erectile problems. Less foreskin covering the glans penis was associated with fewer early ejaculation and erectile problems. Age was found to have a non-linear relationship with early ejaculation and erectile problems in this cross-sectional study. Specifically, early ejaculation problems increased up to a certain age (31) and then decreased with further increases in age. In conclusion, the relationship between the anatomical characteristics of the penis and sexual function was complex. Also, the results suggest that there is a curvilinear non-monotonic relationship between age and sexual dysfunction.

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“…The 5-item diagnostic tool Checklist for Early Ejaculation Symptoms (CHEES), which was developed from three earlier ejaculation diagnostic tools and has improved validity [58], was used to measure the ejaculation control of the participants. This measure has been proven to perform well in differentiating men with and without PE in a Western population sample (AUC = 0.98) [58] and to have a good internal reliability of 0.760 [59]. It has not previously been used with Chinese samples.…”

Section: Checklist For Early Ejaculation Symptoms (Chees)mentioning

confidence: 99%

Associations between Self-Reported Anatomical Characteristics of the Penis and Sexual Dysfunction in Men

Niu,

Ventus,

Jern

et al. 2023

Sexes

Self Cite

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Premature ejaculation and erectile dysfunction are common male sexual dysfunctions worldwide, causing substantial distress in men as well as their partners and decreasing the quality and stability of romantic relationships. We investigated the associations between the self-reported anatomical characteristics of penises and sexual dysfunctions in an urban sample of Chinese men. We recruited 1085 Chinese urban men aged from 18 to 50 (M = 31.37; SD = 5.52) to fill out an online questionnaire regarding the anatomical characteristics of their penis, as well as early ejaculation and erectile problems via two Chinese online survey platforms. The participants reported their age, height, weight, penile length, penile circumference, circumcision status, and foreskin characteristics as well as answered the International Index of Erectile Function-5 and Checklist for Early Ejaculation Symptoms. Both an increasing penile length (M = 14.49; SD = 2.22) and girth (M = 15.46; SD = 4.36) were associated with fewer early ejaculation problems, but only an increasing penile length was associated with fewer erectile problems. Less foreskin covering the glans of the penis was associated with fewer early ejaculation and erectile problems. Age was found to have a non-linear relationship with early ejaculation and erectile problems in this cross-sectional study. Specifically, early ejaculation problems decreased until a certain age (31), and then increased with further increases in age. The relationship between the anatomical characteristics of the penis and sexual function is complex. Also, the results suggest that there is a curvilinear non-monotonic relationship between age and sexual dysfunction.

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Premature Ejaculation Symptoms Are Associated with Sexual Excitability: Empirical Support for the Hyperarousability Model

Cited by 8 publications

References 30 publications

Topological differences of striato‐thalamo‐cortical circuit in functional brain network between premature ejaculation patients with and without depression

Topological differences of striato‐thalamo‐cortical circuit in functional brain network between premature ejaculation patients with and without depression

Associations between Self-Reported Anatomical Characteristics of the Penis, Age and Sexual Dysfunction in Men

Associations between Self-Reported Anatomical Characteristics of the Penis and Sexual Dysfunction in Men

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