Premature mortality due to breast cancer among Canadian women: an analysis of a 30-year period from 1980 through 2010

Pham, Truong-Minh; Sikdar, Khokan C.; Kaposhi, Bethany; Lupichuk, Sasha; Yang, Huanming; Shack, Lorraine

doi:10.1093/eurpub/ckx195

Cited by 13 publications

(16 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, according to our previous study, Canadian women with breast cancer in 1980 lost an average of about one‐fourth of their lifespan when compared to the general population. Conversely, they lost only one‐fifth of their lifespan 30 years later . In other words, women with breast cancer gained about 5 percentage points of lifespan over the period of interest.…”

Section: Discussionmentioning

confidence: 99%

“…[17][18][19] As described in previous studies, we proposed a novel measure called ALSS in addition to existing life-lost indicators. [9][10][11] The calculation of YLL over a long period required several different life tables, which made the comparison over time of the total YLL and AYLL more challenging. Therefore, our new ALSS measure allows for a more intuitive interpretation of the findings.…”

Section: Discussionmentioning

confidence: 99%

“…Conversely, they lost only one-fifth of their lifespan 30 years later. 10 In other words, women with breast cancer gained about 5 percentage points of lifespan over the period of interest. Unfortunately, a similar magnitude of improvement was not seen for head and neck cancers in the present study.…”

Section: Discussionmentioning

confidence: 99%

“…To address the aforementioned comparability issue, we recently proposed a novel measure of premature mortality. We refer to this as average lifespan shortened (ALSS), which is the ratio of the actual YLL to the expected lifespan for individuals if they had not died prematurely of a particular health condition …”

Section: Introductionmentioning

confidence: 99%

“…We refer to this as average lifespan shortened (ALSS), which is the ratio of the actual YLL to the expected lifespan for individuals if they had not died prematurely of a particular health condition. [9][10][11] To our knowledge, there have been no previous studies investigating the long-term trends of premature mortality for head and neck cancers in Canada. Our study aimed to use national mortality data to estimate premature mortality caused by head and neck cancers from 1980 through 2010 and to demonstrate the utility of our new premature mortality measure of ALSS.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Premature deaths due to head and neck cancers in canada: A nationwide analysis from 1980 to 2010

et al. 2019

Self Cite

View full text Add to dashboard Cite

Objectives/Hypothesis To examine if there has been a reduction in premature mortality due to head and neck cancers and their subtypes in the Canadian population between 1980 and 2010. Study Design Retrospective database review. Methods Mortality data for head and neck cancers were obtained from the World Health Organization's mortality database. Years of life lost (YLL) was calculated according to Canadian life tables. A new measure, average lifespan shortened (ALSS), was calculated as a ratio of YLL over the expected lifespan. Results During the period of interest, decreases in age standardized rates of death adjusted to the World Standard Population were observed mainly among men. The adjusted YLL rates remained unchanged with respect to oral cancers in women, but slightly decreased for oral cancers in men and for laryngeal cancers in both sexes. Our new measure of ALSS showed that in 1980, patients with oral cancers lost an average of 20% of their lifespan, whereas in 2010, men and women still lost approximately 20% and 18%, respectively. Patients with laryngeal cancers lost 18% of their lifespan in both sexes in 1980 and 17% in 2010. The ALSS subanalysis showed that the largest gain of lifespan was observed for cancers of the hypopharynx in men and for cancers of the floor of mouth and nasopharynx in women. Conclusions There appears to be modest improvements in premature mortality due to head and neck cancers in Canada over a 30‐year period, with the exception of oral cancers in men. Changes in premature mortality varied slightly by cancer subtypes. Level of Evidence NA Laryngoscope, 130:911–917, 2020

show abstract

Section: Discussionmentioning

confidence: 99%