Premature Sebaceous Hyperplasia in a Neonate

Sebaceous lesions and their associated syndromes: Part I

“…29 It should be noted that these lesions may be seen as early as birth, although they are considered to be a physiologic rather than a pathologic phenomenon in that time frame. 31 Histologically, SH appears as an array of well differentiated, mature sebaceous lobules consisting of sebocytes (Fig 1). 10,19 One or two layers of peripheral basaloid, germinative cells are seen at the periphery of the lobules.…”

“…Several rare forms of SH exist, including giant, linear, diffuse, functional familial (premature), 31 and juxtaclavicular beaded lines. [44][45][46][47][48][49][50] The giant form of SH has been reported several times.…”

“…49 Lesions may occur on the face, chest, and upper back. 31,49,50,56 The patient's skin is typically very oily. 49 The periorbital, perinasal, and preauricular areas are characteristically spared.…”

“…47,48 Functional familial SH, which has also been termed premature or diffuse SH, occurs in young adults of both sexes, and it may run in families. 31,49,50,55,56 The age of onset is typically around puberty. 31,49,50,56 The lesions are thick and diffuse plaqueelike, with pores that resemble an orange peel ( peau d'orange appearance).…”

“…31,49,50,55,56 The age of onset is typically around puberty. 31,49,50,56 The lesions are thick and diffuse plaqueelike, with pores that resemble an orange peel ( peau d'orange appearance). 49 Lesions may occur on the face, chest, and upper back.…”