Premedication for ambulatory surgery in preschool children: a comparison of oral midazolam and rectal thiopentone

Lyons, Barry; Cregg, Nuala; Conway, Frances; Casey, William; Doherty, P.; Moore, Kevin

doi:10.1007/bf03011683

Cited by 8 publications

(4 citation statements)

References 19 publications

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“…Whether midazolam premedication delays discharge in day patients is disputed. Several authors found this is not the case ( 4, 6, 11, 12), whereas others, as we did, found the discharge time somewhat delayed ( 7, 10). Our institution does not use a formal scoring system as a method for determining fitness for discharge.…”

Section: Time To Dischargecontrasting

confidence: 59%

Distress at induction of anaesthesia in children. A survey of incidence, associated factors and recovery characteristics

Carlin

1998

Pediatric Anesthesia

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This study analysed the frequency of distress at induction (DAI) in 2122 paediatric patients. The data were analysed to assess predictors of DAI and to examine associations between predictors of DAI and recovery characteristics. Patient age, preoperative behaviour, premedication (oral midazolam, n = 480) and venue for anaesthesia induction were associated with changes in the incidence of DAI. Distressed preoperative behaviour was a good predictor of DAI in all age groups. Premedication reduced the incidence of DAI in children aged 0.5-2 years old, and in older children who were distressed preoperatively. Induction in the Day Surgery Unit was associated with a reduction of the incidence of DAI in younger children. Children with DAI were more likely to suffer from distress at arousal (P = 0.001). Average early recovery time was prolonged 4.4 minutes and average discharge time in day patients was delayed 36 minutes by the use of oral midazolam premedication. Premedication was not significantly associated with arousal distress. We conclude that a policy of optimizing nonpharmacological approaches for minimizing induction distress, combined with selective premedication with oral midazolam, can produce a low incidence of induction distress and adverse effects.

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Section: Time To Dischargecontrasting

confidence: 59%

Distress at induction of anaesthesia in children. A survey of incidence, associated factors and recovery characteristics

Carlin

1998

Pediatric Anesthesia

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“…When considering the 11 high quality RCTs that examined this question, all showed a benefit. 5,9,10,17,18,23,[26][27][28][29][30] Accordingly, very consistent level 1 evidence indicates that induction anxiety is ameliorated by oral midazolam. Again, the less well designed studies were more variable in their results.…”

Section: Induction Anxietymentioning

confidence: 96%

Mise à jour basée sur des données probantes: Améliore-t-on le comportement des enfants par une prémédication au midazolam par la bouche?

Cox

Nemish

Ewen

et al. 2006

Can J Anesth/J Can Anesth

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“…There are many indications for preoperative sedation in the ambulatory pediatric surgical patient. The large quantity of literature published on premedication for children suggests that the search for the ideal agent has not yet produced a universally satisfactory drug (11–16). The precise goals of premedication must be examined.…”

Section: Discussionmentioning

confidence: 99%

The effect of premedication with OTFC, with or without ondansetron, on postoperative agitation, and nausea and vomiting in pediatric ambulatory patients*

Binstock¹,

Rubin²,

Bachman³

et al. 2004

Pediatric Anesthesia

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Even though OTFC reduced early postoperative agitation the increase in side effects, namely PONV and prolonged recovery times, limits its clinical usefulness. The study demonstrates the tradeoffs between anxiety and agitation vs vomiting, respiratory events and prolonged recovery times. Ambulatory pediatric patients undergoing procedures in which opioids would be routinely used might benefit the most from OTFC combined with ondansetron as part of the anesthetic technique.

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Premedication for ambulatory surgery in preschool children: a comparison of oral midazolam and rectal thiopentone

Cited by 8 publications

References 19 publications

Distress at induction of anaesthesia in children. A survey of incidence, associated factors and recovery characteristics

Distress at induction of anaesthesia in children. A survey of incidence, associated factors and recovery characteristics

Mise à jour basée sur des données probantes: Améliore-t-on le comportement des enfants par une prémédication au midazolam par la bouche?

The effect of premedication with OTFC, with or without ondansetron, on postoperative agitation, and nausea and vomiting in pediatric ambulatory patients*

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