Premenstrual syndrome: a short review

Abstract

Premenstrual syndrome (PMS) is a complex cluster of physical and behavioral symptoms that occur during the late luteal phase of the menstrual cycle in reproductive age women. PMS is inextricably associated with ovulation. Not only pregnancy blocks premenstrual symptoms but also in anovulatory cycles symptoms seem to disappear. It is diagnosed in up to 80% women, worldwide, with around 8% of women suffering from its most severe form -premenstrual disphoric disorder. Although this syndrome has been investigated for almost 60 years, researchers are still far from full understanding of this psycho-somatic condition. Some even question its biological basis and attribute it to specific role that women play in western society and culture. This short review summarizes past and current scientific perspective on PMS, including its etiology and physiology. This paper also discusses evolutionary hypotheses proposed to explain the universal occurrence of premenstrual symptoms in women worldwide.