Prenatal diagnosis and management of sacrococcygeal teratoma and a review of literature

Alalfy, Mahmoud; Ebrashy, Alaa; Idris, Omaima; Azmy, Osama; Zakaria, Ahmed; Elgazzar, A. S.; Gaafar, Hasan; Magdy, Ebrahem; Abbassy, Amr; Hosney, Adel; eleslam, Seif; Kotby, Ahmed; Hasanen, Mohamed; Karoura, Mahmoud; Ezz, Mohamed

doi:10.15406/ogij.2019.10.00412

Cited by 3 publications

(4 citation statements)

References 13 publications

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“…SCTs may be associated with other congenital anomalies such as polydactyly, talipes calcaneovarus, encephalocele, anorectal malformation, omphalocele, sacral agenesis, syndactyly, and renal and cardiac malformations [4,9,17,18]. The differential diagnoses of SCTs are sacral myelomeningocele or meningocele, fibro-lipoma, embryonal rhabdomyosarcoma, anterior meningocele, neurofibroma, cystic hemangioma or lymphangioma, rectal duplication cysts, anal gland cysts, intracanalicular epidermoid tumors, dermal sinus stalks, hydromyelia, external Wilms tumors, retrorectal hamartomas, neuroblastomas, and pacinomas [4,8,9,17,19]. Type I tumors are the most common worldwide and in Nigeria [3,4,10,11], just as in our patient.…”

Section: Discussionmentioning

confidence: 99%

“…Clinical assessment and radiologic imaging are the mainstay of diagnosis of SCTs [1,3,4,10,20]. Current investigation modalities include the use of Computed Tomography (CT) scans and MRI [8,17,21]. While CT scans delineate the lumbosacral and pelvic bony architecture well, MRI is better at delineating the soft tissue architecture.…”

Section: Discussionmentioning

confidence: 99%

“…SCTs are diagnosed prenatally using routine 2-dimensional, advanced 3-dimensional and doppler ultrasonography, as well as ultrafast MRI [6,15,17,21], thus enabling anticipated delivery and early commencement of appropriate treatment. Treatment options include intra-uterine decompression of cystic teratomas [22] and planned early operative delivery of the fetus [17,21]. Early diagnosis and treatment of SCTs are important to prevent malignant transformation, estimated at 5% before one month of age, 60% by one year, and 75% after one year [5,7].…”

Section: Discussionmentioning

confidence: 99%

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Sacrococcygeal teratoma in Nigerians: A case report and clinico-pathologic review

AK¹,

ME²,

KN³

et al. 2022

J Clin Images Med Case Rep

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Introduction: Sacrococcygeal Teratomas (SCTs) are rare childhood tumors, commonly seen in the neonatal period. The mainstay of their diagnosis is both clinical and radiological. Early gross-total surgical excision has the best prognostic outcome, especially for benign tumors. Case report: We present the case of a 12-year old girl with recurrent infected right gluteal benign SCT who was successfully managed in a secondary-level health facility in Nigeria. She has remained symptom-free with no recurrence four years post-surgery. We also reviewed the medical literature on SCT in Nigeria. Discussion: Our case report and others from Nigeria are consistent with the global trend on SCTs. They mostly occur within the first 15 years of life, with a bimodal peak in the first 4 years and at 8-11 years. 75-90% are benign, and the tumors often contain tissues from the three germ layers. Complete surgical excision is the treatment of choice. Conclusion: SCTs are rare tumors, but require early diagnosis and complete surgical excision to prevent malignant transformation. The case report draws attention to the need for a multi-institutional tumor registry in Nigeria and other sub-Saharan African countries. Keywords: sacrococcygeal teratoma; surgical excision; nigeria; literature review.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Sacrococcygeal teratoma in Nigerians: A case report and clinico-pathologic review

AK¹,

ME²,

KN³

et al. 2022

J Clin Images Med Case Rep

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“…The presence of SCT in the same period of time (47th weeks), when cloaca is subdivided by the urorectal septum to form the anorectal canal and the primitive urogenital sinus, could prevent fusion of the genital folds, resulting in a bifid scrotum or hypospadias. The most commonly observed anorectal defects are: imperforate anus, anorectal stenosis and common vertebral anomalies are: sacral hemivertebrae, absence of the sacrum and coccyx [6].…”

Section: Associated Anomaliesmentioning

confidence: 99%

Prenatal Diagnosis and Management of Sacrococcygeal Teratomas

Budusan¹,

Gocan²,

Popa-Stănilă³

2019

Basic Principles and Practice in Surgery

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Sacrococcygeal teratomas (SCT) represents a group tumors deriving from the primordial germ cells. It is the most common tumor affecting neonates, with a female to male ratio of almost 4:1.78. SCT are either benign (mature) or malignant (immature) with different outcome. With advancements in ultrasonography, more SCT are diagnosed prenatally. magnetic resonance imaging (MRI) is more accurate in describing the intrapelvic and abdominal extent of the tumor. Most fetal teratomas could be managed by planned delivery and postnatal surgery. The earlier the diagnosis and surgical intervention, the better the prognosis. A complete surgical excision of the tumor is necessary, including coccygectomy, to prevent recurrence. At the time of birth, most lesions are benign and surgical resection can be accomplished with relatively low morbidity and mortality. Recurrence is reported as 2-35% in patients with immature teratomas, tumor spillage, incomplete resection or failure to remove the coccyx. A long-term follow-up is required for any urinary or bowel dysfunction.

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Fetal Counselling for Surgical Congenital Malformations

Lakhoo

Black

2023

Pediatric Surgery

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Prenatal diagnosis and management of sacrococcygeal teratoma and a review of literature

Cited by 3 publications

References 13 publications

Sacrococcygeal teratoma in Nigerians: A case report and clinico-pathologic review

Sacrococcygeal teratoma in Nigerians: A case report and clinico-pathologic review

Prenatal Diagnosis and Management of Sacrococcygeal Teratomas

Fetal Counselling for Surgical Congenital Malformations

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