Prenatal diagnosis improves the prognosis of children with obstructive uropathies

Schwoebel, Marcus G.; Sacher, Peter; Bucher, Hans Ulrich; Hirsig, J.; Stauffer, U. G.

doi:10.1016/s0022-3468(84)80446-7

Cited by 17 publications

(4 citation statements)

References 9 publications

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“…A detailed prenatal US focusing on the fetal pelvic anatomy will provide anatomic details and facilitate appropriate prenatal counseling to parents [4]. Early US diagnosis improves the prognosis especially in children with associated complication of obstructive uropathy [5]. The initial diagnosis of pelvis mass in both of our patients was done by prenatal US.…”

Section: Discussionmentioning

confidence: 99%

Two Neonates with Congenital Hydrocolpos

Murthy

Costalez

Weiner

et al. 2013

Case Reports in Pediatrics

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Introduction. Neonatal hydrocolpos is a rare condition. Hydrocolpos is cystic dilatation of the vagina with fluid accumulation due to a combination of stimulation of secretary glands of the reproductive tract and vaginal obstruction. The differential for a neonatal presentation of lower abdominal mass includes urogenital anomalies, Hirschsprung's, disease or sacrococcygeal teratoma. Prenatal diagnosis and early newborn imaging studies leads to early detection and treatment of these cases. Case. We report here two cases of neonatal hydrocolpos with prenatal diagnosis of lower abdominal mass. Postnatally, ultrasound, MRI imaging, and cystoscopy confirmed large cystic mass as hydrocolpos with distal vaginal obstruction. Both patients had enlarged renal system secondary to mass effect. Conclusion. High index of suspicion for hydrocolpos in a newborn presenting with fetal diagnosis of infraumbilical abdominal mass will facilitate timely intervention and prevention of complications.

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Section: Discussionmentioning

confidence: 99%

Two Neonates with Congenital Hydrocolpos

Murthy

Costalez

Weiner

et al. 2013

Case Reports in Pediatrics

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“…Authors have reported on whether or not antenatal diagnosis, made on fetuses with congenital malformations, contributed to fe tal outcome [15][16][17][18], As for cases of obstruc tive uropathies, prenatal diagnosis followed by early intervention may improve the long term outcome of these children [15,16]. Simi larly, early recognition of the existence of arrhythmia, early accurate diagnosis and prompt well-controlled drug treatment offer good prospects for continuing the pregnancy to term, and avoiding intrauterine and neona tal death from supraventricular tachycardias [17], On the contrary, the results of shunt pro cedures for obstructive hydrocephalus were less encouraging, because, although 34 of the 44 fetuses survived, only 12 (35.3%) were found to be developing normally [18].…”

Section: Discussionmentioning

confidence: 99%

How Antenatal Ultrasound Diagnosis of Congenital Malformations Has Contributed to Fetal Outcome: A 22-Year Review

et al. 1993

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We herein reviewed 630 malformed fetuses delivered from 24 weeks of gestation onwards in our institute over the past 22 years. These fetuses were divided into 2 groups: 210 from 1970 to 1982 (group 1) and 420 from 1983 to 1991 (group 2). Twenty-two varieties of congenital malformations were diagnosed antenatally in group 1, whereas 55 additional malformations became diagnosable in group 2. Thirty-four varieties of congenital malformations still remained undiagnosed throughout the 22-year study period. Cases receiving ‘fetal therapy’ and ‘close obstetric care’ increased, with statistical significance, from 1.8 to 15.7%, and from 22.9 to 55.7% in groups 1 and 2, respectively. A significant increase was also noted in the survival rate from group 1 (63.3%: 105/166) to group 2 (75.5%: 259/343). This study has revealed that the steady advancement in antenatal diagnosis of congenital malformations, along with great efforts in terms of intensive care, has contributed to improved fetal outcome.

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“…In healthy newborn the dismembered pyeloplasty was performed during the first week in I case and within the first month in 2. Early postnatal surgery with decompression ofthe obstructive uropathies is generally advocated (10).…”

Section: Discussionmentioning

confidence: 99%

The Diagnosis and Course of Antenatal Urinary Tract Dilatation

Cm¹,

Jörgensen²

1986

Eur J Pediatr Surg

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During 1980-1984 the ultrasound examination (US) performed in the third trimester revealed urinary tract dilatation in 18 foetuses. After delivery all the infants were reexamined within the first weeks with US, intravenous pyelography and micturition urethrocystography to confirm the malformation. Pelvic dilatation was seen in 12 foetuses, 5 bilaterally. The dilatation was caused by pelviureteric obstruction in 6 infants, 4 of which were operated on with dismembered pyeloplasty. In 6 infants the dilatation was caused by distal ureteric stenoses, and 5 of them were operated on. Two foetuses with dilated pelvis and ureter had distal ureteric stenosis and both were operated. Four infants with the diagnosis of unilateral multicystic kidney, confirmed postnatally, were nephrectomised. At the follow-up the kidney function was normal in 15 infants and slightly decreased in 3 infants with bilateral malformations. The antenatal US revealed pelvic dilatation, but the diagnosis of a dilated ureter was inaccurate. Prenatal urinary tract dilatation should be controlled via US shortly after delivery and, if persistent, evaluated further by means of x-ray examinations.

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Prenatal diagnosis improves the prognosis of children with obstructive uropathies

Cited by 17 publications

References 9 publications

Two Neonates with Congenital Hydrocolpos

Two Neonates with Congenital Hydrocolpos

How Antenatal Ultrasound Diagnosis of Congenital Malformations Has Contributed to Fetal Outcome: A 22-Year Review

The Diagnosis and Course of Antenatal Urinary Tract Dilatation

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