Prenatal diagnosis of congenital varicella syndrome and detection of varicella-zoster virus in the fetus: a case report

Hartung, J.; Enders, Gisela; Chaoui, Rabih; Arents, A.; Tennstedt, C.; Bollmann, Rainer

doi:10.1002/(sici)1097-0223(199902)19:2<163::aid-pd483>3.0.co;2-9

Cited by 33 publications

(17 citation statements)

References 3 publications

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“…Successful use of ultrasound as a diagnostic tool to identify this syndrome prenatally has also been reported in cases with evidence of widespread infection [273][274][275][276]. Three published reports indicate, however, that ultrasound is not infallible.…”

Section: Fetal Malformations and Management Of Pregnant Women With Vamentioning

confidence: 99%

Chickenpox, Measles, and Mumps

Gershon¹

2011

Infectious Diseases of the Fetus and Newborn

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Section: Fetal Malformations and Management Of Pregnant Women With Vamentioning

confidence: 99%

Chickenpox, Measles, and Mumps

Gershon¹

2011

Infectious Diseases of the Fetus and Newborn

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“…However, the infection, which can be confirmed by amniotic fluid or fetal blood test for viral DNA, and fetal histopathological change, as miliary calcified necroses in fetal organs, are confirmed. [26] Prenatal diagnosis on the problem can be presently done. Nevertheless, it is confirmed that chicken pox can have vertical transmission mode.…”

Section: Effect Of Chicken Pox On Pregnancymentioning

confidence: 99%

“…[25] Usually, the mother gets the infection at term and the infant present with specific vesicular skin lesion confirming the appearance of congenital chicken pox. [2627] Acyclovir treatment of the affected neonate with congenital chicken pox is also recommended. [2627] Indeed, the serious congenital infection might be preventable with passive antibody prophylaxis and antiviral therapy.…”

Section: Vertical Transmission Of Chicken Poxmentioning

confidence: 99%

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Chicken pox in pregnancy : An obstetric concern

Wiwanitkit

2010

Indian J Dermatol

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Chicken pox is a common viral infection presenting with fever and discrete vesicular lesions. This infection can be widely detected in developing countries, especially for those tropical countries. The pregnant can get chicken pox, and this becomes an important obstetrical concern. In this specific paper, the author hereby details and discusses on chicken pox in pregnancy. Clinical presentation, diagnosis, treatment, and prevention are briefly summarized. In addition, the effects of chicken pox on pregnancy as well as the vertical transmission are also documented.

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“…Nach Verfügbarwerden der PCR konnte Varicella-zoster-Virus-DNA nicht nur im Bläschenin-halt, sondern auch in Amnionflüssigkeit, fetalem Blut, und fetalen Geweben nachgewiesen werden [5]. Obwohl bei Fällen mit kongenitalem Varizellensyndrom eine Virusreplikation noch zum Zeitpunkt der Geburt in Betracht gezogen wurde, ist bisher nicht eindeutig geklärt, ob von den Neugeborenen mit CVS eine potenzielle Infektionsgefahr für die Umgebung ausgeht.…”

Section: Introductionunclassified

Kongenitales Varizellensyndrom - besteht eine Infektionsgefahr für die Umgebung?

Schulze-Oechtering

Roth²,

Enders³

et al. 2004

Z Geburtshilfe Neonatol

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A 30-year-old gravida 2 suffered from chickenpox in the 13th week of gestation. In the 38th week of gestation she delivered by caesarean section a baby with typical congenital varicella syndrome (CVS). In the serum of the newborn IgG antibodies but no IgM or IgA antibodies were found by VZV ELISA test (Enzygnost Behring). On the 2nd, 5th, 8th and 11th days of life, VZV DNA was detectable in the cerebrospinal fluid by PCR in elevated copy numbers as well as in the fluid of skin lesions on the 3rd day of life in higher copy numbers, on the 11th day of life it was still detectable in low copy numbers. In the EDTA blood samples taken on the 5th day of life VZV DNA was detectable in low copy numbers. The positive VZV DNA detection in skin lesions led to the conclusion that newborns with CVS and skin lesions should be considered as infectious until the time of crusting and isolated in nursery care.

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Prenatal diagnosis of congenital varicella syndrome and detection of varicella-zoster virus in the fetus: a case report

Cited by 33 publications

References 3 publications

Chickenpox, Measles, and Mumps

Chickenpox, Measles, and Mumps

Chicken pox in pregnancy : An obstetric concern

Kongenitales Varizellensyndrom - besteht eine Infektionsgefahr für die Umgebung?

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