Prenatal diagnosis of diastematomyelia

Sonigo-Cohen, Pascale; Schmit, Pierre; Zérah, Michel; Chat, Latifa; Simon, Isabelle; Aubry, Marie Cécile; Gonzalès, Marie; Pierre-Kahn, Alain; Brunelle, Françis

doi:10.1007/s00381-003-0771-8

Cited by 38 publications

(23 citation statements)

References 14 publications

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“…These abnormalities had not been seen on prenatal MR images or conventional postnatal sequences. Sonigo-Cohen et al [30] reported 3 cases in which the diagnosis of split cord malformation was made on prenatal MR images, in which there was minimal or no bony structure around the lesion. In cases with a large bony septum, however, it is difficult to differentiate neural tissue from these structures, and postnatal hT2WI is helpful in detecting subtle abnormal findings like split cord malformation or syringohydromyelia, which may require surgical intervention.…”

Section: Discussionmentioning

confidence: 99%

Clinical Significance of Prenatal and Postnatal Heavily T2-Weighted Magnetic Resonance Images in Patients with Myelomeningocele

et al. 2015

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Purpose: To compare the utility and limitations of prenatal magnetic resonance (MR) imaging using half-Fourier acquisition single-shot turbo spin-echo (HASTE) with postnatal heavily T2-weighted imaging (hT2WI) for the evaluation of central nervous system abnormalities associated with myelomeningocele (MMC). Methods: Sixteen patients with MMC who had undergone pre- and postnatal MR imaging were included in this study. MR imaging, including HASTE, was undertaken in the 3rd trimester, and hT2WI was performed immediately after delivery. The precision with which each could distinguish MMC, hindbrain herniation and ventriculomegaly was compared retrospectively. Results: The skin defects and MMC sacs were clearly visible on prenatal HASTE images, although it was difficult to identify precisely the level of MMC compared with postnatal hT2WI, in which the detailed anatomical relationships of the spinal cord, neural placode and ventral nerve roots were evident in every case. Hindbrain herniation could be visualized on prenatal HASTE images, although its severity was difficult to evaluate because of the small size of the structures and neck flexion; again, the resolution was superior on postnatal hT2WI. For hydrocephalus, there were no significant differences in the diagnostic precision and ability to grade the severity between pre- and postnatal imaging. Conclusion: Prenatal HASTE imaging permits the diagnosis and understanding of the gross anatomy of MMC and associated hindbrain herniation and ventriculomegaly, but postnatal hT2WI is superior for evaluating detailed anatomy.

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Section: Discussionmentioning

confidence: 99%

Clinical Significance of Prenatal and Postnatal Heavily T2-Weighted Magnetic Resonance Images in Patients with Myelomeningocele

et al. 2015

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“…La diastématomyélie est une malformation rare d'étiologie inconnue qui est isolée ou associée à des anomalies vertébra-les, viscérales ou à d'autres types de dysraphismes spinaux [5]. Les formes isolées sont souvent de bon pronostic [6].…”

Section: Discussionunclassified

“…Sur 35 cas de diastématomyélie actuellement décrits dans la littérature, l'IRM foetale a été utilisée comme examen complémentaire dans cinq cas. Pour chaque cas, elle a confirmé le diagnostic sans apporter d'éléments supplémentaires par rapport au diagnostic écho-graphique [5,6,[10][11][12]. L'intérêt de l'IRM anténatale pour le diagnostic des anomalies rachidiennes reste encore discuté.…”

Section: Discussionunclassified

Diastématomyélie: difficultés du diagnostic anténatal

Hannebicque-Montaigne

Chaffiotte

Joriot

et al. 2010

Rev. med. perinat.

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La diastématomyélie est une malformation rachidienne rare caractérisée par la présence d'un éperon médian fibreux ou osseux séparant la moelle en deux hémimoelles. Nous rapportons le cas d'une diastématomyélie diagnostiquée à l'échographie anténatale morphologique. Le diagnostic a été confirmé par l'imagerie par résonance magnétique (IRM) postnatale, alors que l'IRM anténatale évoquait le diagnostic de myélolipome lombosacré. Le diagnostic anté-natal repose sur des signes échographiques spécifiques. Nous discutons de l'intérêt de l'IRM foetale, faite en seconde intention, dans l'évaluation du diagnostic et du pronostic de cette malformation. Pour citer cette revue : Rev. Méd. Périnat. 2 (2010). Mots clés Diastématomyélie · Diagnostic anténatal · IRM foetale · Dysraphisme spinalAbstract Diastematomyelia is a rare spinal malformation characterized by a cleft in the spinal cord caused by a sagittal osseous or fibrocartilaginous spur. We report a case of prenatal diagnosis of diastematomyelia on a routine second-trimester sonography. Postnatal MRI confirmed the diagnosis, whereas fetal MRI detected a lumbosacral lipoma. Diastematomyelia can be diagnosed antenatally with highly specific sonographic signs. We discuss the interest of antenatal MRI, made in second intention, to specify the diagnosis and the prognosis of this malformation. To cite this journal: Rev. Méd. Périnat. 2 (2010).

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“…Scan of the fetal thoracolumbar region (see text for details). The differential diagnosis of diastematomyelia includes other types of dysraphism, isolated meningocele, and intraspinal lipoma [11] . A maternally increased AFP level is a good marker for prenatal diagnosis screening of neural tube defects including diastematomyelia.…”

Section: Discussionmentioning

confidence: 99%

Prenatal Diagnosis of Diastematomyelia in a 15-Week-Old Fetus

Bırı¹,

Turp²,

Kurdoğlu³

et al. 2005

Fetal Diagn Ther

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Objective: A case of prenatal diagnosis of diastematomyelia is presented. Methods: A case of fetal diastematomyelia, diagnosed by prenatal sonography, demonstrated the typical sonographic features of this condition. In this case it was detected at 15 weeks of gestation, and presented with a midline echogenic focus in the posterior region of the thoracolumbar spine. Results: The pregnancy was terminated by induction of labor. The fetus was female and there was a 1-cm long endurated hyperemic lesion at the back of the fetus. We confirmed the diagnosis of diastematomyelia after termination of pregnancy by plain chest and abdominal X-ray and also MRI scanning. Conclusion: Isolated diastematomyelia is a rare form of spinal dysraphism characterized by a sagittal cleft in the spinal cord, conus medullaris and/or filum terminale with splaying of the posterior vertebral elements. Prenatal diagnosis of this anomaly is possible in the early mid-trimester by sonography, thus allowing for early surgical intervention and a favorable prognosis.

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Prenatal diagnosis of diastematomyelia

Cited by 38 publications

References 14 publications

Clinical Significance of Prenatal and Postnatal Heavily T2-Weighted Magnetic Resonance Images in Patients with Myelomeningocele

Clinical Significance of Prenatal and Postnatal Heavily T2-Weighted Magnetic Resonance Images in Patients with Myelomeningocele

Diastématomyélie: difficultés du diagnostic anténatal

Prenatal Diagnosis of Diastematomyelia in a 15-Week-Old Fetus

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