Prenatal diagnosis of foetal hydrocephalus and suspected X-linked recessive inheritance of cleft lip in a Chihuahua

Abstract

A 3.5-year-old, 2.9 kg, multiparous Chihuahua presented with abdominal distension; pregnancy was diagnosed. On Day 7 before parturition, prenatal sonograms showed anechoic bilateral dilated cerebral lateral ventricles, suggesting fluid-filled regions (ventriculomegaly) in one foetus. A Caesarean section was performed and the male newborn had an abnormally enlarged dome-shaped head and a cleft lip, and died 6 days after birth. According to the family pedigree, the X-linked recessive inheritance of an orofacial cleft from the unaffected mother was suggested. This report clearly demonstrates that canine foetal ventriculomegaly (hydrocephalus) can be diagnosed in utero. For dog breeds predisposed to congenital ventriculomegaly, early detection is important for the prediction of perinatal survival and adequate supportive care can be applied at delivery.

Apgar score or birthweight in Chihuahua dogs born by elective Caesarean section: which is the best predictor of the survival at 24 h after birth?

“…To the authors’ knowledge, Chihuahua newborns do not need a targeted Apgar score, as it was done for French Bulldog by Vilar et al, [ 20 ], as the heart rate and the other parameters reported in literature [ 20 , 22 ] are in agreement with the Apgar score introduced by Veronesi et al [ 13 ].…”

Sebaceous Adenoma Case in a Golden Retriever Dog

“…Faktor-faktor yang berkontribusi dari munculnya tumor ini adalah paparan radiasi ultraviolet dalam jangka panjang (Lesnik et al, 1992) serta penurunan ekspresi reseptor estrogen dan progesteron pada kelenjar sebasea (Ginel et al, 2010). Diagnosis de nitif dari adenoma sebasea memerlukan pemeriksaan sitologi ataupun melalui histopatologi (Marques-da- Costa et al,2015;Sabattini et al, 2015;Sananmuang et al, 2016). Tindakan eksisi bedah saja bersifat kuratif mengingat sifat biologis tumor adalah jinak.…”

“…Tindakan eksisi bedah saja bersifat kuratif mengingat sifat biologis tumor adalah jinak. Tidak ada laporan adanya metastasis dari tumor ini, dan kemungkinan transformasi dari lesi jinak menjadi ganas juga belum dilaporkan (Sananmuang et al, 2016). Laporan kasus ini menyajikan kejadian adenoma sebasea berupa ulser pada anjing ras Golden Retriever.…”

“…Hewan yang terdampak rata-rata berumur sekitar 9,5 tahun, dengan rentang empat bulan hingga 16 tahun (Pakhrin et al, 2007). Belum ada laporan mengenai progresi adenoma sebasea menjadi bentuk ganas (Sananmuang et al, 2016). Terdapat beberapa ras yang memiliki predisposisi jenis tumor ini,…”

Prenatal Diagnosis of Canine and Feline Twins Using Ultrasound: A Retrospective Study

“…Normal foetal development can be assessed by observing the chronologic relationship between organ development and gestation, which is also useful for determining the date of delivery [10][11][12][13][14][15][16], and embryonic/foetal disorders can be predicted by observing a delay in the time of development of the organs or alterations in their appearance, or by finding a slow rate of foetal growth [17][18][19]. Single reports of foetal abnormalities diagnosed early using ultrasound have been reported, both in canine and feline species, including monochorionic twins [20,21], hydrops fetalis [22][23][24][25][26][27][28], hydrocephalus [29,30], clefts [31], and kidney defects [32].…”