2016
DOI: 10.1002/pds.4072
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Prenatal exposure to antidepressants and risk of epilepsy in childhood

Abstract: Antidepressant use during pregnancy was associated with a higher risk of epilepsy among children whose mothers had also a registry-based hospital diagnosis of depression during pregnancy. Copyright © 2016 John Wiley & Sons, Ltd.

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Cited by 15 publications
(25 citation statements)
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“…as the main reason of the hospital contact. Approach 1 5 , 10 and approach 2 6 , 11 has been used in several papers conducted by authors of this study. In Figure 1 we used mock data for nine persons to illustrate the categorization of diagnoses (a primary or secondary diagnosis, a referral diagnosis, and an associated diagnosis), groups of persons according to their diagnoses (group 1, 2, and 3), detailed procedures of identifying patients of interest by approach 1 and 2, and persons identified by approach 1 and 2.…”
Section: Methodsmentioning
confidence: 99%
“…as the main reason of the hospital contact. Approach 1 5 , 10 and approach 2 6 , 11 has been used in several papers conducted by authors of this study. In Figure 1 we used mock data for nine persons to illustrate the categorization of diagnoses (a primary or secondary diagnosis, a referral diagnosis, and an associated diagnosis), groups of persons according to their diagnoses (group 1, 2, and 3), detailed procedures of identifying patients of interest by approach 1 and 2, and persons identified by approach 1 and 2.…”
Section: Methodsmentioning
confidence: 99%
“…The occurrence of disorders of the autism spectrum in particular is subject to special attention. The child may then have withdrawal symptoms (symptômes de sevrage) which vary depending on the drug [23][24][25]. Recently, a Danish team examined the link between taking an antidepressant during pregnancy and the occurrence of epilepsy in children.…”
Section: Mental Health Disorders Depression and Womenmentioning
confidence: 99%
“…Taking an antidepressant only in the months before pregnancy but not during pregnancy also increased the risk of epilepsy in children. In utero exposure to antidepressants and seems associated with an increased risk of epilepsy in children [24].…”
Section: Mental Health Disorders Depression and Womenmentioning
confidence: 99%
“…On average, males have a marginally higher incidence of epilepsy than females while generalized epilepsies are more common among females and epilepsy with focal seizure are more common among males [ 5 ]. Epilepsy has a high degree of heritability indicating shared genetic components in epileptogenesis [ 6 8 ], but intrauterine factors like maternal preeclampsia [ 9 ], infections [ 10 ], and medication use in pregnancy [ 11 ] have also been associated with risk of epilepsy. Whether prenatal exposure to subtle differences in sex hormones plays a role in the development of epilepsy remains uncertain [ 12 ].…”
Section: Introductionmentioning
confidence: 99%