2000
DOI: 10.1016/s0165-3806(00)00085-7
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Prenatal methotrexate exposure delays onset of low Mg2+-induced epileptiform discharges in the entorhinal cortex

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Cited by 2 publications
(3 citation statements)
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“…50 Similarly, there was an increased resistance to low Mg 2+ -induced epileptiform activity in slices from prenatally MTX-exposed rats. 51 There was no sex difference in these effects of prenatal MTX. Morphologically, we observed increased cellularity in parts of the cortex 51 as well as clusters of GABAergic cells in the neocortex (FIG.…”
Section: Examples Of Models Of Prenatal Drug Exposurementioning
confidence: 93%
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“…50 Similarly, there was an increased resistance to low Mg 2+ -induced epileptiform activity in slices from prenatally MTX-exposed rats. 51 There was no sex difference in these effects of prenatal MTX. Morphologically, we observed increased cellularity in parts of the cortex 51 as well as clusters of GABAergic cells in the neocortex (FIG.…”
Section: Examples Of Models Of Prenatal Drug Exposurementioning
confidence: 93%
“…If a single dose of 5 mg/kg was administered on E15, the offspring invariably demonstrated increased resistance to evoked seizures, i.e., this exposure had anticonvulsant features 50 . Similarly, there was an increased resistance to low Mg 2+ ‐induced epileptiform activity in slices from prenatally MTX‐exposed rats 51 . There was no sex difference in these effects of prenatal MTX.…”
Section: Introductionmentioning
confidence: 98%
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