Journal of Ultrasound in Medicine

2006

DOI: 10.7863/jum.2006.25.1.115

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Prenatal Sonographic Diagnosis of Grebe Syndrome

Dwight R. Cordero¹,

Yael Goldberg²,

et al.

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Cardiovascular Disease and Preventive Healthcare after Organ Transplantation

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,

²

2014

Textbook of Organ Transplantation

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No abstract

Cardiovascular Disease and Preventive Healthcare after Organ Transplantation

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²

2014

Textbook of Organ Transplantation

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Grebe dysplasia — prenatal diagnosis based on rendered 3-D ultrasound images of fetal limbs

¹

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²

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³

et al. 2016

Pediatr Radiol

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Grebe dysplasia is a rare skeletal dysplasia characterized by severe acromesomelic shortening of the long bones in a proximal to distal gradient of severity, with bones of the hands and feet more severely affected than those of the forearms and legs, which in turn are more severely affected than the humeri and femora. In addition, the bones of the lower extremities tend to be more severely affected than the bones of the upper extremities. Despite the severe skeletal deformities, the condition is not lethal and surviving individuals can have normal intelligence. Herein we report a case of Grebe dysplasia diagnosed at 20 weeks of gestation. Rendered 3-D ultrasound images of the fetal limbs, particularly of the characteristic tiny and globular-looking fingers and toes, were instrumental in accurately characterizing the phenotype prenatally.

The Fetal Musculoskeletal System

et al. 2008

Ultrasonography in Obstetrics and Gynecology

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No abstract

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