Prenatally Detected Hepatic Hamartoma: Another Cause of Non‐immune Hydrops

Bessho, Takefumi; Kubota, Kozo; KOMORI, SHINJI; Ohtsuka, Yoshitoshi; Uneo, Yuji; Uematsu, Kazuyoshi; Koyama, Koji

doi:10.1002/(sici)1097-0223(199604)16:4<337::aid-pd848>3.3.co;2-l

Cited by 5 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prenatal HMH is usually detected by ultrasound in the third trimester. These lesions have been associated with polyhydramnios, fetal hydrops, intrauterine fetal demise and preterm labor [3,9]. In neonates, HMH may cause life-threatening abdominal distension and respiratory distress [8].…”

Section: Hepatic Mesenchymal Hamartomamentioning

confidence: 99%

Hepatic mesenchymal hamartoma and undifferentiated embryonal sarcoma of the liver: a pathologic review

Martins-Filho

Putra

2020

Hepat. Oncol.

View full text Add to dashboard Cite

This review highlights two rare entities that are predominantly seen in children: hepatic mesenchymal hamartoma (HMH) and undifferentiated embryonal sarcoma of the liver (UESL). HMH is a benign lesion predominantly seen in the first 2 years of life, while UESL is malignant and usually identified in patients between 6 and 10 years of age. UESL may arise in the background of HMH, and the association has been supported by similar chromosomal aberrations (19q13.4). The diagnosis of both lesions is primarily based on histologic evaluation, as the clinical and radiological features are not always typical. The clinicopathologic characteristics, pathogenesis, differential diagnoses and treatment for both lesions are discussed.

show abstract

Section: Hepatic Mesenchymal Hamartomamentioning

confidence: 99%

Hepatic mesenchymal hamartoma and undifferentiated embryonal sarcoma of the liver: a pathologic review

Martins-Filho

Putra

2020

Hepat. Oncol.

View full text Add to dashboard Cite

show abstract

“…Other symptoms include vomiting, decreased appetite and poor bodyweight gain. Complications, such as heart failure due to arterioveneous shunting 6 , respiratory distress/failure, obstructive jaundice related to tumour compression, or HMH associated with non‐immune hydrops diagnosed postnatally have been reported 7 . In the present case reports, the patients mainly presented with abdominal distension and/or mass, and there were no complications noted.…”

Section: Discussionmentioning

confidence: 50%

Hepatic mesenchymal hamartoma

2003

J Paediatrics Child Health

View full text Add to dashboard Cite

Hepatic mesenchymal hamartoma (HMH) is a rare liver tumour in childhood. It is believed to be a benign tumour with a good prognosis if the tumour is excised. Only a few cases with local relapse or metastasis have been reported. We reviewed 134 patients with space-occupying liver lesions, from January 1990 to December 1999, and four patients with HMH were found. Abdominal mass and/or distension were the common initial presentations. Three of our four cases were diagnosed in the first year of life. The liver function tests and tumour markers were non-specific. Case 1 underwent tumour enucleation and another three cases underwent tumour excision. One patient died. No tumour recurrence was noted in the surviving patients.

show abstract

“…However fatal complications are associated with big tumors when they present as large space-occupying abdominal masses causing respiratory distress, circulatory problems, and occasionally fetal hydrops. [80][81][82][83] High output congestive heart failure occurs as the result of arteriovenous shunting through the tumor. 83 Hepatoblastoma is seldom diagnosed in the perinatal period.…”

Section: Discussionmentioning

confidence: 99%

Fetal Hydrops Associated with Tumors

Isaacs

2008

Amer J Perinatol

View full text Add to dashboard Cite

Fetuses with tumors associated with hydrops have a high mortality rate. Relatively few survivors have this potentially fatal combination. This study examined the clinical and pathological findings, pathogenesis, and outcomes of fetuses with tumors and hydrops. One hundred and fifty-eight study cases were collected from the literature and from personal files. Only patients where adequate clinical and pathological data were given and the outcome of pregnancy was described were included in the study. Cardiac tumors were the majority found in association with fetal hydrops. Leukemia and extracardiac teratomas were next in frequency followed by hepatic tumors, neuroblastoma, placental, soft tissue, and renal tumors. The main presenting findings along with hydrops were hydramnios, a tumor mass, placentomegaly, and stillbirth. Most tumors were detected in the third trimester of pregnancy. No fetus with the diagnosis of cardiac rhabdomyoma, neuroblastoma, brain tumor, rhabdoid tumor, or histiocytosis associated with hydrops survived. Those patients with placental chorangioma, pericardial teratoma, and hepatic hemangioma had the best outcome. The overall survival rate was low: 30 of 158 (19%).

show abstract

Prenatally Detected Hepatic Hamartoma: Another Cause of Non‐immune Hydrops

Cited by 5 publications

References 0 publications

Hepatic mesenchymal hamartoma and undifferentiated embryonal sarcoma of the liver: a pathologic review

Hepatic mesenchymal hamartoma and undifferentiated embryonal sarcoma of the liver: a pathologic review

Hepatic mesenchymal hamartoma

Fetal Hydrops Associated with Tumors

Contact Info

Product

Resources

About