Preoperative and postoperative levels of interleukin-6 in patients with acute appendicitis: comparison between open and laparoscopic appendectomy

Abstract

The operative stress in open as compared with laparoscopic appendectomy is not reflected by circulating levels of IL-6.

Serum levels of fibroblast growth factor‐21 are increased in chronic and acute renal dysfunction

“…parameter (ratio) = parameter postsurgery /parameter presurgery similar to other studies. 19 Univariate correlation analysis was performed by Spearman's rank correlation method using these relative changes (ratios). Afterwards, multivariate linear regression analysis was performed as described previously.…”

“…In study population 2, differences in FGF‐21 serum concentrations and other laboratory parameters before and after renal surgery were assessed by Wilcoxon signed‐rank test for related samples. Furthermore, relative changes (postsurgical‐to‐presurgical ratios) were calculated for all laboratory parameters as follows: parameter (ratio) = parameter postsurgery /parameter presurgery similar to other studies . Univariate correlation analysis was performed by Spearman's rank correlation method using these relative changes (ratios).…”

An evaluation of the utility of additional tests in the preoperative diagnostics of acute appendicitis

“…Presumably, the concentration of IL-6 in blood increases after surgery in correlation with the degree of surgical stress; but in perforated appendicitis, this leads to an IL-6 expression rate more than 2.5-times that of the reference levels in 90% of such patients [11][12][13]. Despite the promising results of systematic reviews devoted to the use of IL-6 in AA diagnosis, the nature of the enzyme-linked immunosorbent (ELISA) method means that it will not be available in routine tests in admissions for some time.…”

Are Neutrophil CD64 Expression and Interleukin-6 Early Useful Markers for Diagnosis of Acute Appendicitis?

“…IL-6 is a mediator of the inflammatory response and early marker of tissue damage. 2,30 Eriksson et al also reported a very high serum concentration of IL-6 in patients with complicated appendicitis. 26 Kharbanda et al believe that an understanding of the fluctuations in biomarker levels in relation to the duration of abdominal pain may be clinically useful.…”