“…Mortality and morbidity associated with preoperative anxiety are more likely due to major cardiovascular problems associated with health-related behaviors such as smoking, poor diet, poor compliance with treatment, or an inactive lifestyle and direct in uence on the myocardial perfusion, autonomic nervous system regulation, platelet activation, increased hypothalamus-pituitary-adrenal axis activity and exaggerated in ammatory processes (3,4,7,8,12,13,17,26,41,44,45,50,51,57,(59)(60)(61)(62)(63)(64). However, the body of evidence on global prevalence and determinates of preoperative anxiety among surgical patients is still in demand.…”