Preoperative assessment of blood supply and its role in predicting anastomotic leak

Khan, Sualeh Muslim; Wells, Cameron I.; Christou, Niki; Tan, Chee Yang; Mathur, Pawan; El‐Hussuna, Alaa

doi:10.1016/j.surg.2023.04.001

Cited by 3 publications

(1 citation statement)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Anastomotic leak is a significant complication of colorectal surgery that carries high morbidity and mortality. Even when surgery is performed by experienced surgeons, leak rates can range from 2 to 7% (6). The pathophysiology of leak is still unclear with several large knowledge gaps around cause and prevention.…”

Section: Project 3: Understanding Anastomotic Leak By Implementing Ma...mentioning

confidence: 99%

Peak performance in surgery: how machine learning can improve surgical performance

El-Hussuna

2024

Impact Surgery

View full text Add to dashboard Cite

Surgical research is associated with specific methodological and practical challenges related to the assessment of complex interventions and variation of clinical equipoise. Biases can, to some degree, be overcome by randomisation, blinding, and intervention standardisation, although randomised trials can be costly and time-consuming. This poses a unique opportunity for innovation in surgical research design and evaluation to improve both validity of surgical trials and their assessment. There are many examples of challenging topics in surgical research, and despite thousands of studies, robust evidence is still elusive. Many of those challenges might be addressed by implementing Machine Learning approach.

show abstract

Section: Project 3: Understanding Anastomotic Leak By Implementing Ma...mentioning

confidence: 99%

Peak performance in surgery: how machine learning can improve surgical performance

El-Hussuna

2024

Impact Surgery

View full text Add to dashboard Cite

show abstract

Indocyanine green in left side colorectal surgery segmental resection to decrease anastomotic leak: A parallel retrospective cohort study of 115 patients

Romboli,

Orlandi,

Citterio

et al. 2024

Heliyon

View full text Add to dashboard Cite

Applications of indocyanine greenenhanced fluorescence in the laparoscopic treatment of colonic stricture after necrotizing enterocolitis

Die,

Cui,

Feng

et al. 2023

BMC Pediatr

View full text Add to dashboard Cite

Background The status of anastomotic blood perfusion is associated with the occurrence of anastomotic leakage after intestinal anastomosis. Fluorescence angiography (FA) with indocyanine green (ICG) can objectively assess intestinal blood perfusion. This study aims to investigate whether anastomotic perfusion assessment with ICG influences surgical decision-making during laparoscopic intestinal resection and primary anastomosis for colonic stricture after necrotizing enterocolitis. Methods Patients who underwent laparoscopic intestinal resection and primary anastomosis between January 2022 and December 2022 were retrospectively analyzed. Before intestinal anastomosis, the ICG fluorescence technology was used to evaluate the blood perfusion of intestinal tubes on both sides of the anastomosis. After the completion of primary anastomosis, the anastomotic blood perfusion was assessed again. Results Of the 13 cases, laparoscopy was used to determine the extent of the diseased bowel to be excised, and the normal bowel was preserved for anastomosis. The anastomosis was established under the guidance of ICG fluorescence technology, and FA was performed after anastomosis to confirm good blood flow in the proximal bowel. The anastomotic intestinal tube was changed in one case because FA showed a difference between the normal range of intestinal blood flow and the macroscopic prediction. There was no evidence of ICG allergy, anastomotic leakage, anastomotic stricture, or other complications. The median follow-up was 6 months, and all patients recovered well. Conclusions The ICG fluorescence technology is helpful in precisely and efficiently determining the anastomotic intestinal blood flow during stricture resection and in avoiding anastomotic leakage caused by poor anastomotic intestinal blood flow to some extent, with satisfactory short-term efficacy.

show abstract

Preoperative assessment of blood supply and its role in predicting anastomotic leak

Cited by 3 publications

References 21 publications

Peak performance in surgery: how machine learning can improve surgical performance

Peak performance in surgery: how machine learning can improve surgical performance

Indocyanine green in left side colorectal surgery segmental resection to decrease anastomotic leak: A parallel retrospective cohort study of 115 patients

Applications of indocyanine greenenhanced fluorescence in the laparoscopic treatment of colonic stricture after necrotizing enterocolitis

Contact Info

Product

Resources

About