Preoperative Chronic Kidney Disease as a Strong Predictor of Postoperative Infection and Mortality After Coronary Artery Bypass Grafting

Minakata, Kenji; Bando, Ko; Tanaka, Shiro; Takanashi, Shuichiro; Konishi, Hiroaki; Miyamoto, Yoshihiro; Ueshima, Kenji; Yasuno, Shinji; Ueda, Yuichi; Okita, Yutaka; Masuda, Izuru; Okabayashi, Hitoshi; Yaku, Hitoshi; Okamura, Yoshitaka; Tanemoto, Kazuo; Arinaga, Koichi; Hisashi, Yosuke; Sakata, Ryuzo

doi:10.1253/circj.cj-14-0328

Cited by 36 publications

(29 citation statements)

References 27 publications

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“…4 Minakata et al also found that advanced preoperative renal failure is a strong predictor of postoperative outcomes after CABG. 19 Our study clarified a direct correlation between lower renal function and aggravated LVDD.…”

Section: 72supporting

confidence: 54%

Predictors and Clinical Impacts of Aggravated Left Ventricular Diastolic Dysfunction After Off-Pump Coronary Artery Bypass Grafting

Lee

Kim

Joo

et al. 2016

Circ J

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Section: 72supporting

confidence: 54%

Predictors and Clinical Impacts of Aggravated Left Ventricular Diastolic Dysfunction After Off-Pump Coronary Artery Bypass Grafting

Lee

Kim

Joo

et al. 2016

Circ J

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“…The incidence of deep sternal wound infection in our total patient group (non-elderly and elderly patients combined) was 1.4% (36/2,618), which was comparable to the 1.6% (25/1,518) documented in a previous multicenter study. 23 The incidence of deep sternal wound infection in our total non-elderly patients who underwent BIMA grafting was 1.9% (12/634). The incidence of deep sternal wound infection in our Elderly BIMA Group was 4.7% (5/107) and higher than the 1.0% (3/292) in our Elderly SIMA Group.…”

Section: Disclosuresmentioning

confidence: 76%

Is Bilateral Internal Mammary Arterial Grafting Beneficial for Patients Aged 75 Years or Older?

Itoh

Kimura

Adachi

et al. 2016

Circ J

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Background: Although bilateral internal mammary artery (BIMA) grafting is performed with increasing regularity in elderly patients, whether it is truly beneficial, and therefore indicated, in these patients remains uncertain. We retrospectively investigated early and late outcomes of BIMA grafting in patients aged ≥75 years. Methods and Results:We identified 460 patients aged ≥75 years from among 2,618 patients who underwent either single internal mammary artery (SIMA) grafting (n=293) or BIMA grafting (n=107). Early outcomes did not differ between the SIMA and BIMA patients (30-day mortality: 1.7% vs. 0%, P=0.39; sternal wound infection: 1.0% vs. 4.7%; P=0.057). Late outcomes, 10-year survival in particular, were improved in the BIMA group (36.6% vs. 48.1%, P=0.033). In the analysis of the results in propensity score-matched groups (196 patients in the SIMA group, 98 patients in the BIMA group), improved 10-year survival was documented in the BIMA group (34.8% vs. 47.6%, P=0.030). Cox proportional regression analysis showed SIMA usage (non-use of BIMA) to be a predictor for late mortality (hazard ratio: 0.65, 95% confidence interval: 0.43-0.98, P=0.042). We further compared outcomes between the total non-elderly patients (n=2,158) and total elderly patients (n=460). BIMA usage was similar, as was 30-day mortality (1.0% vs. 1.3%, respectively). Conclusions:A survival advantage, with no increase in early mortality, can be expected from BIMA grafting in patients aged ≥75 years. (Circ J 2016; 80: 1756 -1763

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“…worsens as CKD progresses, which is associated with the inflammatory response, activation of the renin-angiotensinaldosterone system, electrolyte disturbance, hypertension, dyslipidemia, nephrogenic anemia, left ventricular hypertrophy, and endothelial dysfunction. [8][9][10][11][12][13][14][15][16][17][18] In this study, all patients had DM and the prevalences of moderate and severe CKD were 31.6% and 14.3%, respectively. These rates were higher than in the STS database report (moderate CKD, 24%; severe CKD, 2.5%).…”

Section: Discussionmentioning

confidence: 93%

“…Minakata et al reported a similar result whereby severe CKD including HD was an independent risk factor for developing any infection. 16 Deo et al showed that harvesting BITA with a skeletonized technique is not associated with DSWI because it can minimize tissue damage, and preserve the blood supply to the sternum. 28 Therefore, the present lower incidence of DSWI even in DM patients may be mainly attributable to the skeletonized technique.…”

Section: Discussionmentioning

confidence: 99%

Impact of Chronic Kidney Disease on Long-Term Outcome of Coronary Artery Bypass Grafting in Patients With Diabetes Mellitus

Ohira

Doi

Numata

et al. 2016

Circ J

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Preoperative Chronic Kidney Disease as a Strong Predictor of Postoperative Infection and Mortality After Coronary Artery Bypass Grafting

Cited by 36 publications

References 27 publications

Predictors and Clinical Impacts of Aggravated Left Ventricular Diastolic Dysfunction After Off-Pump Coronary Artery Bypass Grafting

Predictors and Clinical Impacts of Aggravated Left Ventricular Diastolic Dysfunction After Off-Pump Coronary Artery Bypass Grafting

Is Bilateral Internal Mammary Arterial Grafting Beneficial for Patients Aged 75 Years or Older?

Impact of Chronic Kidney Disease on Long-Term Outcome of Coronary Artery Bypass Grafting in Patients With Diabetes Mellitus

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