“…Hepatic metastasis complicates 20-30% of colorectal cancer cases [1,2], Recent advances in imaging tech niques facilitate accurate identification of the number, size and location of hepatic metastasis for planning surgi cal procedures [3,4], During the last decade, numerous reports have confirmed that 25 to 40% of patients treated by hepatic resection have a 5-year survival [5][6][7], How ever, despite a significant improvement over the results of unresectable hepatic metastasis in recent years, 5-year survivors are still rare [8,9], There are two types of hepatic metastasis: synchronous hepatic metastasis, which is diagnosed within 6 months after the diagnosis of colorectal carcinoma as defined by Attiveh et al [10], and metachronous hepatic metastasis, manifesting evident hepatic metastasis during the follow up periods after colorectal resection. In the latter type of metastasis, despite the fact that no visible metastasis is recognized at the time of colorectal surgery, it is possible that micrometastasis exists in the liver.…”