Preoperative disinfection of the conjunctival sac with antibiotics and iodine compounds: A prospective randomized multicenter study

Abstract

Three-day administration of LVFX ophthalmic solution and use of an eyewash with diluted iodine compounds is effective for preoperative disinfection. However, complete elimination of bacteria from the conjunctival sac is difficult.

Changes in drug susceptibility and the quinolone-resistance determining region of Staphylococcus epidermidis after administration of fluoroquinolones

“…These agents have a potent antibacterial activity and broad antibacterial spectrum with high levels of tissue distribution and safety. Although the most recent studies report that administering eyedrops for 3 days before surgery significantly reduces bacteria in the conjunctival sac compared with administration for 1 day or 1 hour before surgery, 8 there is no established instillation protocol during the perioperative and postoperative period. Thus, the instillation is usually performed based on the empirical practice of each surgeon.…”

Survey of practice preference pattern in antibiotic prophylaxis against endophthalmitis after cataract surgery in Singapore

“…Literature in support of the use of topical preoperative prophylaxis have shown a reduction in the number of ocular surface flora [18,19], and achievement of therapeutic intraocular concentrations of antibiotics, especially newer fourth-generation fluoroquinolones such as moxifloxacin and gatifloxacin [20,21]. Nevertheless, in Singapore, a variety of topical preoperative antibiotics were used, including tobramycin, a bactericidal aminoglycoside, the bacteriostatic chloramphenicol, and levofloxacin and moxifloxacin.…”

Minimum endotoxin concentration causing inflammation in the anterior segment of rabbit eyes

“…Prevention of postoperative infection is one important factor, although there are not so many cases. 23 A major complication is postoperative infl ammation. The blood-aqueous barrier (BAB) function plays an important role in postoperative infl ammation in the anterior segment of the eye.…”