Preoperative Evaluation of Abnormal Mammographic Findings to Avoid Unnecessary Breast Biopsies

Abstract

Rigorous mammographic evaluation and the use of stereotactic biopsy for selected lesions can prevent breast biopsy for low-suspicion mammographic abnormalities while still allowing the detection of early-stage breast cancer.

Cytoplasmic vacuolation, intracytoplasmic lumina, and DPAS staining in ductal carcinoma of the breast

“…16 The nuclear features are sufficiently discriminatory for separating benign and malignant lesions. However, the existence of cytological findings that discriminate between ductal carcinoma in situ and invasive ductal carcinoma has not been unanimously accepted.…”

The Negative Predictive Value of Electrical Impedance Scanning in BI-RADS Category IV Breast Lesions

“…[2][3][4] For the mammographic category IV final assessment, the PPV is reported to be 30 -34%. 5,6 In our study sample, the PPV of BI-RADS category IV was 28.9%.…”

“…Several studies have shown that the positive predictive value (PPV) for biopsies performed because of mammographic findings is 15-40%. [2][3][4] For the category IV final assessment, the PPV is reported to be 30 -34%. 5,6 This high rate of false-positive mammograms results in a correspondingly high rate of unnecessary biopsies that impose a heavy psychologic burden on women and a heavy financial cost on the health care system.…”

Extent of Lumpectomy for Breast Cancer After Diagnosis by Stereotactic Core Versus Wire Localization Biopsy

“…Because of the high index of suspicion of these lesions, some clinicians recommend an open biopsy to obtain a definitive diagnosis, because a nondiagnostic reading of a stereotactic core biopsy would not avoid the need for a subsequent open biopsy. [11][12][13] Our study, as well as reports by others, suggests that there are several reasons why stereotactic core biopsy may be advantageous for even the highly suspicious lesions. 9 -14 From the cost standpoint, Yim et al 1 and Whittin et al 15 have reported that stereotactic core biopsy reduced the number of surgical procedures performed per patient.…”