Preoperative evaluation of Klatskin tumor: accuracy of spiral CT in determining vascular invasion as a sign of unresectability

H., J.; Han, Joon Koo; Kim, T. K.; Kim, A. Y.; Park, S. J.; Choi, Byung Ihn; Suh, Kyung Suk; Kim, S. W.; Han, Man Chung

doi:10.1007/s002610000081

Cited by 52 publications

(35 citation statements)

References 3 publications

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“…Multidetector CT (MDCT) scan offers excellent spatial resolution and fast scanning and optimally depicts relation of the tumor with hepatic artery and portal vein [26,27] . Multiplanar reformats (MPR) and maximum and minimum intensity projections are useful in accurately demonstrating ductal and vascular invasion (Figure 4).…”

Section: Ctmentioning

confidence: 99%

Imaging and interventions in hilar cholangiocarcinoma: A review

Madhusudhan

Gamanagatti

Gupta

2015

WJR

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Hilar cholangiocarcinoma is a common malignant tumor of the biliary tree. It has poor prognosis with very low 5-year survival rates. Various imaging modalities are available for detection and staging of the hilar cholangiocarcinoma. Although ultrasonography is the initial investigation of choice, imaging with contrast enhanced computed tomography scan or magnetic resonance imaging is needed prior to management. Surgery is curative wherever possible. Radiological interventions play a role in operable patients in the form of biliary drainage and/or portal vein embolization. In inoperable cases, palliative interventions include biliary drainage, biliary stenting and intra-biliary palliative treatment techniques. Complete knowledge of application of various imaging modalities available and about the possible radiological interventions is important for a radiologist to play a critical role in appropriate management of such patients.We review the various imaging techniques and appearances of hilar cholangiocarcinoma and the possible radiological interventions. Core tip: Poor prognosis of hilar cholangiocarcinoma mandates early diagnosis. The article outlines the performance of various imaging modalities in making a diagnosis and allows the readers to decide the appropriately modality in a given case. Further, the brief descriptions of a wide range of radiological interventions in hilar cholangiocarcinoma educate the readers about the available options and choose them judiciously.

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Section: Ctmentioning

confidence: 99%

Imaging and interventions in hilar cholangiocarcinoma: A review

Madhusudhan

Gamanagatti

Gupta

2015

WJR

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“…In dynamic contrast-enhanced CT, the arterial and portal-venous enhancement phases are separated, and the vascular structures can be displayed such that CT angiography using MDCT provides vascular details equivalent to those with catheter angiography in detecting clinically relevant anatomy of the hepatic arteries and portal vein in the context of preoperative planning for tumor resection [33,[37][38][39]. Regarding detection of small lymph node and peritoneal metastases, CT has limited sensitivity of approximately 50% for N2 metastases [37].…”

Section: Hilar and Distal Extrahepatic Cholangiocarcinomamentioning

confidence: 99%

“…Regarding detection of small lymph node and peritoneal metastases, CT has limited sensitivity of approximately 50% for N2 metastases [37]. The overall accuracy of CT for assessing resectability is in the range of 60%-75% [37,38,40]. …”

Section: Hilar and Distal Extrahepatic Cholangiocarcinomamentioning

confidence: 99%

What Is the Current State-of-the-Art Imaging for Detection and Staging of Cholangiocarcinoma?

Slattery

Sahani

2006

The Oncologist

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Cholangiocarcinoma is an adenocarcinoma that arises from the bile duct epithelium and is the second most common primary hepatobiliary cancer, after hepatocellular cancer, with approximately 2,500 cases annually in the U.S. However, cholangiocarcinoma remains a relatively rare disease, accounting for <2% of all human malignancies. Although the entire biliary tree is potentially at risk, tumors involving the biliary confluence or the right or left hepatic ducts (hilar cholangiocarcinoma) are most common and account for 40%-60% of all cases. Most patients present with advanced disease that is not amenable to surgical treatment. The median survival time for patients with intrahepatic cholangiocarcinoma without involvement of the hilum varies among centers from 18-30 months. The median survival time for patients with perihilar cholangiocarcinoma is slightly less, varying from 12-24 months. Despite the overall poor prognosis, survival after surgical treatment of hilar cholangiocarcinoma has improved during the past 10-15 years. This review highlights the imaging features of cholangiocarcinoma, with particular emphasis on the imaging techniques that can best assess tumor resectability and guide the surgeon regarding the potential extent of resection required in operable candidates. The Oncologist 2006;11:913-922

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“…Najczęściej są to raki (cholangiocarcinoma) z nabłonka przewodów żółciowych [1][2][3][4], rzadziej natomiast formy niezłośliwe: brodawczaki, gruczolaki, nerwiaki lub guzy typu GIST. Ze względu na lokalizację można wyróżnić raka połączenia przewodów płatowych wątroby (guz Klatskina lub guz wnęki wątroby), raki przewodowe (przewodu żółciowego wspólnego, przewodu wątrobowego) oraz raka brodawki Vatera, który zwykle jest omawiany odrębnie [1][2][3][5][6][7]. W ponad połowie przypadków raka przewodów zewnątrzwątrobowych guz zlokalizowany jest przywnękowo oraz po równo w odcinku środkowym i przydwunastniczym lub wystę-puje wieloogniskowo [5,6,8].…”

Section: Introductionunclassified

“…Ocena stopnia zaawansowania raka dróg żółcio-wych oraz określenie resekcyjności odgrywa podstawową rolę w kwalifikowaniu pacjentów do leczenia operacyjnego [7,13]. Tomografia komputerowa (TK) jest metodą obrazową zalecaną jako pojedyncze narzę-dzie w diagnostyce guzów dróg żółciowych.…”

Section: Introductionunclassified

Biliary tract carcinoma – determination of therapeutic possibilities in the imaging evaluation of tumor progression

Ćwik¹,

Krupski²,

Prystupa³

et al. 2013

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Preoperative evaluation of Klatskin tumor: accuracy of spiral CT in determining vascular invasion as a sign of unresectability

Abstract: Spiral CT is a reliable method for detecting vascular invasion and unresectable tumors. However, it has limitations in detecting variations of the bile duct or the intraductal extent of tumor.

Cited by 52 publications

References 3 publications

Imaging and interventions in hilar cholangiocarcinoma: A review

Imaging and interventions in hilar cholangiocarcinoma: A review

What Is the Current State-of-the-Art Imaging for Detection and Staging of Cholangiocarcinoma?

Biliary tract carcinoma – determination of therapeutic possibilities in the imaging evaluation of tumor progression

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