Preoperative Evaluation of Living Kidney Donors With Multidetector Computed Tomography Angiography

Petridis, Anastasios; Papachristodoulou, Athanasia; Geroukis, Triantafyllos; Fouzas, I.; Papanikolaou, Vasilios; Palladas, Panagiotis

doi:10.1016/j.transproceed.2008.08.041

Cited by 12 publications

(5 citation statements)

References 11 publications

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“…Other reports of fibromuscular dysplasia in potential donors identified a prevalence of 3.8% to 4.4% using conventional angiography, with 75% being women (27,28), compared with the 2.7% prevalence by CT angiography in our study (with 81% being women). The 0.6% prevalence of renal artery dilation in our study compares with 1.3% in another study of potential kidney donors (29).…”

Section: Discussioncontrasting

confidence: 48%

Prevalence of Renal Artery and Kidney Abnormalities by Computed Tomography among Healthy Adults

Lorenz¹,

Vrtiska²,

Lieske³

et al. 2010

Clinical Journal of the American Society of Nephrology

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Background and objectives: Management of incidental renal artery and kidney abnormalities in patients undergoing computed tomography scans is a clinical challenge because their frequency in healthy subjects has not been precisely estimated. Therefore, the prevalence and management of these abnormalities were determined among a large cohort of potential kidney donors undergoing protocol evaluations.Design, setting, participants, & measurements: All patients at the Mayo Clinic who underwent computed tomographic angiography and urography as part of their kidney donor evaluation between 2000 and 2008 were identified. Radiographic reports were abstracted for abnormalities of the renal arteries and kidneys. The prevalence of radiographic abnormalities was stratified by age and gender, and the effect on approval for kidney donation was determined.Results: Among 1957 potential kidney donors, the mean ؎ SD age was 43 ؎ 12 years, and 58% were women. The most common abnormalities were kidney stones (11%), focal scarring (3.6%), fibromuscular dysplasia (2.8%), and other renal artery narrowing or atherosclerosis (5.3%). Fibromuscular dysplasia, focal scarring, parenchymal atrophy, and upper tract dilation were more common in women. Renal artery narrowing, focal scarring, and indeterminate masses increased with age. Overall, 25% of potential donors had at least one abnormality. However, these incidental radiographic abnormalities contributed to exclusion from donation in only 6.7% of potential donors.Conclusions: Incidental radiographic abnormalities of the renal arteries and kidneys are common. The majority of imaging findings are not perceived to be harmful enough to prevent kidney donation, but future studies are needed to determine their clinical relevance.

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Section: Discussioncontrasting

confidence: 48%

Prevalence of Renal Artery and Kidney Abnormalities by Computed Tomography among Healthy Adults

Lorenz¹,

Vrtiska²,

Lieske³

et al. 2010

Clinical Journal of the American Society of Nephrology

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“…Multi-detector CT Angiography and Urography (MDCTA/CTU) has replaced conventional angiography for assessment of renal vascular anatomy prior to living donor nephrectomy 1,2 . These studies may image the lung bases, abdomen and pelvis and thus have the potential to detect a wide variety of clinically occult abnormalities which may affect kidney donation.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Incidental Findings on Abdominal Computed Tomography Angiograms on Prospective Renal Donors

et al. 2015

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“…To avoid the impact of individual differences and the increased radiation dose caused by repeated scanning, the bolus tracking method is more frequently used at present. Various reports provide greatly different trigger threshold settings, which ranges from 50 to 200 HU; moreover, there is no detailed description of the effect of different threshold values on the observation of target vessels (Namasivayam et al, 2006;Chai et al, 2008;Petridis et al, 2008;Zamboni et al, 2010). It should be noted that with the increase of the threshold value, the renal vein gradually becomes more obviously developed in the arterial phase scan, which affects the observation of renal arteries, especially the tiny branches.…”

Section: Discussionmentioning

confidence: 99%

Application value of multislice spiral computed tomography angiography in the evaluation of renal artery variation in living donor kidney transplantation

Xiu-yi¹,

Tian²,

Ru³

et al. 2015

Genet. Mol. Res.

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ABSTRACT. This study aims to investigate the accuracy and value of multislice spiral computed tomography (MSCT) angiography in the evaluation of renal artery variation in living donor kidney transplantation. Two hundred seventy-three kidney transplantation donors underwent preoperative MSCT scanning. Two doctors determined the running direction and variation of the renal artery through joint analysis of the preoperative original MSCT image and the recombination image using the blind reading method, compared the imaging results with the intraoperative results, and evaluated the accuracy and application value of MSCT angiography in the evaluation of renal artery variation in living donor kidney transplantation. CT angiography (CTA) can better show the renal artery and its variation. A total of 52 accessory renal arteries were found in the 273 kidney transplant operations, whereas 55 accessory renal arteries were found in preoperative MSCT. Four accessory renal arteries indicated in the MSCT were not found during the operation, and one accessory renal artery found during the operation Renal artery variation in donor kidney transplantation was not indicated in the preoperative MSCT. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of MSCT in the diagnosis of accessory renal arteries were 98.1, 98.2, 92.7, 99.5, and 98.2%, respectively. MSCT angiography can sensitively and accurately show the renal artery and its variation in living donor kidney transplantation, and has important clinical value for the formulation of the operative scheme before the transplantation.

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Preoperative Evaluation of Living Kidney Donors With Multidetector Computed Tomography Angiography

Cited by 12 publications

References 11 publications

Prevalence of Renal Artery and Kidney Abnormalities by Computed Tomography among Healthy Adults

Prevalence of Renal Artery and Kidney Abnormalities by Computed Tomography among Healthy Adults

Prevalence of Incidental Findings on Abdominal Computed Tomography Angiograms on Prospective Renal Donors

Application value of multislice spiral computed tomography angiography in the evaluation of renal artery variation in living donor kidney transplantation

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