2023
DOI: 10.1016/j.jpurol.2023.01.013
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Preoperative hormone therapy in single-stage repair of hypospadias: A comprehensive systematic review

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Cited by 3 publications
(2 citation statements)
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“…We concur with the authors’ perspective that preoperative testosterone administration could lower the incidence of postoperative complications (healing complications, urethral obstruction, urethral diverticula, reoperation rate, etc) in certain subgroups. 2 Nevertheless, reaching a conclusive consensus on its use is still challenging due to variations in its criteria, dosage and duration, children’s age, and hypospadias classifications across institutions. Based on this, future studies on testosterone administration should focus on specific cohorts, as mentioned in the authors' conclusion.…”
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confidence: 99%
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“…We concur with the authors’ perspective that preoperative testosterone administration could lower the incidence of postoperative complications (healing complications, urethral obstruction, urethral diverticula, reoperation rate, etc) in certain subgroups. 2 Nevertheless, reaching a conclusive consensus on its use is still challenging due to variations in its criteria, dosage and duration, children’s age, and hypospadias classifications across institutions. Based on this, future studies on testosterone administration should focus on specific cohorts, as mentioned in the authors' conclusion.…”
mentioning
confidence: 99%
“…3 The adverse effects of testosterone on healing were amplified among nonresponders, in which case androgens can be identified as being repressors of cutaneous repair. 2…”
mentioning
confidence: 99%