Preoperative hyponatremia predicts outcomes after cardiac surgery

Crestanello, Juan A.; Phillips, Gary; Firstenberg, Michael S.; Sai-Sudhakar, Chittoor; Sirak, John; Higgins, Robert S.D.; Abraham, William T.

doi:10.1016/j.jss.2012.06.004

Cited by 33 publications

(42 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The cumulative mid‐term mortality rate was also significantly elevated in the hyponatremia group. The results were in accordance with previous studies which investigated cardiac disease and post‐cardiac surgery outcomes . These findings were thought to reflect the elevation of cardiovascular mortality based on the sub‐analysis model.…”

Section: Discussionsupporting

confidence: 91%

“…This was also confirmed by the Japanese multicenter investigation for heart failure, which showed high rates of cardiovascular death in patients with hyponatremia [10]. The cumulative 1-year mortality rate of 18.7% in the hyponatremia group was considered comparable or superior to the rates in previous reports which ranged from 21.9 to 34.0% [5,9,12,13,18]. Efforts should thus be expended to reduce the risk of future all-cause and cardiac death after TAVR.…”

Section: Discussionsupporting

confidence: 64%

See 1 more Smart Citation

Impact of pre‐procedural hyponatremia on clinical outcomes after transcatheter aortic valve replacement: A propensity‐matched analysis

Kagase

Yamamoto

Shimura

et al. 2018

Cathet Cardio Intervent

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 64%

Impact of pre‐procedural hyponatremia on clinical outcomes after transcatheter aortic valve replacement: A propensity‐matched analysis

Kagase

Yamamoto

Shimura

et al. 2018

Cathet Cardio Intervent

View full text Add to dashboard Cite

show abstract

“…One of the important electrolytes in this field is sodium. Sodium is an important electrolyte in blood pressure maintenance in normal ranges and also the proper function of nerves in muscles (5)(6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

“…Moreover sodium plays a crucial role in hemostats and maintaining the physiology of cardiac muscle cells (7,9). During CPB hypernatremia and hypernatremia with more than 5 meq/L fluctuations may cause complications for patients (10)(11)(12)(13)(14)(15).…”

Section: Introductionmentioning

confidence: 99%

“…During CPB hypernatremia and hypernatremia with more than 5 meq/L fluctuations may cause complications for patients (10)(11)(12)(13)(14)(15). Fluctuations in serum sodium levels are common in patients with heart disease, moreover hyponatremia has been reported as an independent risk factor for morbidity and mortality after cardiac surgery (7). Hyponatremia is induced because of hemodilution during CPB, serums and vasopressors which are applie (15).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Association of Perioperative Serum Sodium Level Fluctuation and Postoperative Complications in Coronary Artery Bypass Graft Surgery

Azarfarin

Shekoohi

Totonchi

et al. 2017

Multidiscip CardioAnnal

View full text Add to dashboard Cite

Background: Electrolyte abnormalities are common in coronary artery bypass graft surgery (CABG) using cardiopulmonary bypass (CPB). Changes in serum sodium (Na) concentration more than 15 meq/L in perioperative period (Delta Na > 15) is considered as significant fluctuation. The aim of this study was evaluating the relationship between the significant fluctuation of serum Na level and the complications after coronary artery bypass graft surgery. Methods: In this prospective observational study 59 patients who were candidates for CABG with CPB were enrolled into the study. We recorded patients' demographic data, arterial blood gas analysis (ABG), serum electrolytes including Na levels from anesthesia induction, during and after CPB up to 24 hours after admission in ICU. Postoperative complications until discharge from ICU were compared between patients with significant Na fluctuation and those without it.Results: Thirty-nine patients had serum sodium fluctuation equal and more than 15 mEq/L (Delta Na ≥ 15 group). This group was compared with those who had minor Na variation (Delta Na < 15; n = 20). The Na > 15 mEq/L fluctuation group had higher serum Na and lactate levels, lower base excess in ABG. Patients with at least one postoperative complication, were older and had lower ejection fraction and more sodium fluctuations. Logistic regression analysis showed that serum sodium fluctuation more than 15mEq/l was independently associated with post CABG complications. Conclusions: Perioperative serum sodium fluctuation more than 15mEq/L was independently associated with postoperative complications in patients undergoing CABG.

show abstract

General Preoperative Considerations and Preparation of the Patient for Surgery

2020

Manual of Perioperative Care in Adult Cardiac Surgery

View full text Add to dashboard Cite

Preoperative hyponatremia predicts outcomes after cardiac surgery

Cited by 33 publications

References 22 publications

Impact of pre‐procedural hyponatremia on clinical outcomes after transcatheter aortic valve replacement: A propensity‐matched analysis

Impact of pre‐procedural hyponatremia on clinical outcomes after transcatheter aortic valve replacement: A propensity‐matched analysis

Association of Perioperative Serum Sodium Level Fluctuation and Postoperative Complications in Coronary Artery Bypass Graft Surgery

General Preoperative Considerations and Preparation of the Patient for Surgery

Contact Info

Product

Resources

About