Preoperative Methicillin-Resistant Staphylococcus aureus Screening in Mohs Surgery Appears to Decrease Postoperative Infections

Abstract

Preoperative MRSA screening and implementation of a decontamination protocol appears to decrease postoperative MRSA wound infections after Mohs surgery. Although an interesting observation, controlled studies of clinical and cost effectiveness are required before general implementation. The authors have indicated no significant interest with commercial supporters.

Antibiotic Stewardship in der Dermatologie – Grundlagen und aktuelle Themen

“…[22,34]. Zwei Studien konnten bereits nachweisen, dass eine Dekolonisation durch topische und systemische Antibiotika sowie präoperative Waschungen nach unterschiedlichem Design zu einer reduzierten Rate an SSI im Rahmen mehrzeitiger dermatochirurgischer Eingriffe führen können [37,38].…”

Surgical Site Infections in Dermatologic Surgery

“…7 The mechanisms of how these bacteria interact among themselves, each other, and with skin in both normal and pathologic skin states are complex; extensive research efforts focus on the role of the skin microbiome and its role in skin homeostasis. 14 Thus, it appears that some SSIs are of endogenous origin. This bacterium has been long regarded as a commensal; recent research has defined its function as a mutualistic organism in enhancing skin innate immunity by the secretion of toxins and antimicrobial peptides that protect the skin from other pathogens and help elicit host immune responses through stimulation of Toll-like receptors.…”

Systematic literature analysis and review of targeted preventive measures to limit healthcare-associated infections by meticillin-resistant Staphylococcus aureus

“…Non-controlled studies implementing decolonisation in non-ICU settings led to a decrease in overall and peristomal MRSA infections [57,76], in the incidence of S.aureus/MRSA SSI in surgical units [55,58,64,65,71,77,79], in overall S. aureus/MRSA infections in gastrointestinal surgery and orthopaedics [49,82], and in the total rate of SSI or wound infections [53,60,67]. [49,76,79], extra-nasal use of mupirocin [69,77,80], selective digestive decontamination [52], povidone-iodine [49], and systemic antibiotics [54].…”