Preoperative Natriuretic Peptide-B Values and Ascites in Male Liver Transplant Recipients

Espinosa, M.D.; Olmedo, C.; Muffak-Granero, K.; Comino, A.; Nogueras, Mabel; Villegas, M.T.; Becerra, A.; Garrote, Daniel; Bueno, Pablo; Ferrón, José Antonio

doi:10.1016/j.transproceed.2011.01.086

Cited by 3 publications

(2 citation statements)

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“…The presence of ascites is correlated with the severity progression and cardiac dysfunction among patients with hepatic cirrhosis. [36,37] Hepatic encephalopathy (HE) associated coma occurring before liver transplant can have a substantial negative impact on post-transplant outcomes. [38] However, the relationship between HE and NODALT has not been investigated.…”

Section: Discussionmentioning

confidence: 99%

Prevalence, predictive factors, and survival outcome of new-onset diabetes after liver transplantation

et al. 2016

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Section: Discussionmentioning

confidence: 99%

Prevalence, predictive factors, and survival outcome of new-onset diabetes after liver transplantation

et al. 2016

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“…In cirrhotic patients, elevated BNP or NT-BNP may reflect systolic dysfunction, left ventricular hypertrophy with subsequent diastolic dysfunction, and increased pulmonary artery pressures with resulting right ventricular overload (8,9,10,12). Elevated BNP or NT-BNP also seems to reflect disease severity, with correlations to presence of ascites, decreased synthetic function, increased hepatic venous presence gradient, and increased Child-Pugh and model for end-stage liver disease (MELD) scores (13). Elevated BNP or NT-BNP has also been implicated as an independent predictor of mortality in advanced cirrhosis (14).…”

Section: Introductionmentioning

confidence: 99%

B-type peptides to predict post–liver transplant mortality: systematic review and meta-analysis

Chahal

Yau

Casciato

et al. 2019

CanLivJ

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BACKGROUND: Cirrhotic patients undergoing liver transplantation are at risk of cardiac complications. Brain natriuretic peptide (BNP) and amino terminal brain natriuretic peptide (NT-BNP) are used in cardiac risk stratification. Their significance in predicting mortality risk in cirrhotic patients during or after liver transplantation is unknown. We conducted a systematic review and meta-analysis to answer this question. METHODS: An electronic search of EMBASE, MEDLINE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews (2005-September 2016), Google Scholar, and study bibliographies was conducted. Study quality was determined, and demographic and outcome data were gathered. Random effects meta-analyses of mortality-based BNP and NT-BNP level or presence of post-transplant heart failure were conducted. RESULTS: Seven studies including 2,010 patients were identified. Demographics were similar between patients with high or low BNP or NT-BNP levels. Hepatitis C was the most prevalent etiology of cirrhosis (38%). Meta-analysis revealed a pooled relative risk of 3.1 (95% CI 1.9% to 5.0%) for post-transplant mortality based on elevated BNP or NT-BNP level. Meta-analysis also revealed a pooled relative risk of 1.6 (95% CI 1.3% to 2.1%) for post-transplant mortality if patients had demonstrated posttransplant heart failure. CONCLUSIONS: Our analysis suggests that BNP or NT-BNP measurement may help in risk stratification and provides data on post-operative mortality in cirrhotic patients undergoing liver transplantation. Discriminatory thresholds are higher in cirrhotic patients relative to prior studies with non-cirrhotic patients. However, the number of analyzed studies is limited, and our findings should be validated further through larger, prospective studies.

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Echocardiographic Study in Cirrhotic Patient Candidates for Liver Transplantation

Espinosa

Nogueras

Olmedo

et al. 2012

Transplantation Proceedings

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Preoperative Natriuretic Peptide-B Values and Ascites in Male Liver Transplant Recipients

Cited by 3 publications

References 5 publications

Prevalence, predictive factors, and survival outcome of new-onset diabetes after liver transplantation

Prevalence, predictive factors, and survival outcome of new-onset diabetes after liver transplantation

B-type peptides to predict post–liver transplant mortality: systematic review and meta-analysis

Echocardiographic Study in Cirrhotic Patient Candidates for Liver Transplantation

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