Although tamsulosin remains the major factor predisposing to IFIS, significant correlations with other factors also exist, such as decreased pupil diameter and the intake of finasteride, benzodiazepines, and antipsychotic agents.
Although tamsulosin remains the major factor predisposing to IFIS, significant correlations with other factors also exist, such as decreased pupil diameter and the intake of finasteride, benzodiazepines, and antipsychotic agents.
“…Axial length is another factor of debate in IFIS [3,16,39]. Safir et al [40 ▪ ] reports that, in addition to decreased mydriatic pupil diameter, increased lens thickness is associated with increased IFIS risk regardless of alpha-antagonist treatment status.…”
Purpose of reviewThe aim of this study was to review and summarize recent findings and advancements regarding intraoperative floppy iris syndrome (IFIS). Although many improvements have been made for the management of IFIS, it remains a challenging condition for surgeons. An understanding of the syndrome as well as the multitude of tools to mitigate risk of complication is important for surgeons operating on highrisk patients.
Recent findingsA variety of management approaches have been modified and improved or further supported with new data, such as intracameral compounds, intraoperative devices and surgical techniques.
SummaryAn understanding of risk factors is important for the identification of at-risk patients. A variety of approaches can greatly reduce incidence of IFIS complications. Multiple management strategies should be utilized to further reduce risk during these difficult surgeries.
“…The association of small pupils and the dreaded intraoperative floppy iris syndrome (IFIS) is well known. A maximum dilation of less than 7 mm is a vulnerability [5,6].…”
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