Preoperative predictors of restoration in quality of life after surgery for lung cancer

Abstract

Background The preoperative predictors of quality of life (QOL) in patients who undergo lung resection for lung cancer are poorly known. Here, we investigated these predictors in such patients using two QOL measures. Methods In this single‐institutional prospective cohort study, we administered the EQ‐5D‐5 levels (EQ‐5D‐5L) from January 2015, and the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire with 30 items from April 2015 to April 2018 preoperatively (Pre) and at one month postoperatively (M1), and one year postoperatively (Y1). General health status was measured by the EQ‐5D visual analogue scale (VAS) and EORTC global health status/QOL (GHS) scores. Multivariable linear regression analyses were used to explore the preoperative predictors of QOL at Y1. Results A total of 223 patients were included in the study. The EQ‐5D VAS and EORTC GHS scores, at Pre, M1, and Y1, were 80 ± 15, 77 ± 15, and 84 ± 11; and 74 ± 19, 65 ± 20, and 78 ± 17, respectively. In the multivariable analyses, the albumin level, preoperative VAS score, and preoperative pain/discomfort and anxiety/depression were identified as predictors by the EQ‐5D VAS score. The preoperative EORTC GHS score, absence of diabetes mellitus, preoperative cognitive function score, and preoperative symptom score of pain were identified as predictors by the EORTC GHS score. Conclusions The EQ‐5D VAS and EORTC GHS scores traced similar trajectories of QOL. In both QOL measures, preoperative pain was found as a common predictor. These predictors may help improve patient/survivor care in the future.

[Retracted] Dynamic Changes and Influencing Factors for the Quality of Life in Nursing Care after Lung Cancer Resection

“…In a study by Ichimura et al [15] on survivors after lung cancer surgery, it was found that postoperative quality of life decreased in approximately 73% of patients due to surgical trauma and pain and approximately 51% of patients could not complete daily life independently due to postoperative immobilization and fatigue. Some scholars have proposed that a high health-related quality of life can be achieved by adjusting the analgesic regimen, adding physical training after lung cancer resection, reducing pain, and diminishing the incidence of postoperative fatigue [16]. e results from the current study verified that the quality of life gradually increased and then stabilized at 3, 6, and 12 months after surgery.…”

Comparison of Postoperative Quality of Life and Pain with and without a Metal Rib Spreader in Patients Undergoing Lobectomy through Axillary Mini-Thoracotomy for Stage I Lung Cancer

“…In our cohort, the VAS score of the less invasive approach (VA/noMRS and AMT/MRS) was 7 points superior to the open approach. 16) This might support our interpretation of this study that both the VA/noMRS and AMT/MRS approaches are less invasive.…”

“…We recently reported on the QOL assessment in a prospective study. 16,17) We used the Japanese version of the EQ-5D-five-levels (EQ-5D-5L) questionnaire (Registration No. 7772) and the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30) as the QOL measures.…”

“…This study was planned as a part of our prospective single-institutional observational study to clarify the patient-reported QOL in surgical patients with lung cancer. 16,17)…”

Effect of Exercise Training on Quality of Life after Colorectal and Lung Cancer Surgery: A Meta-Analysis

“…HRQoL is a multidimensional construct encompassing patients’ perceptions of domains such as physical, emotional, social, and cognitive functions [ 35 ], and these perceptions are influenced not only by exercise capacity [ 20 ], but also by clinical factors such as the administration of adjuvant chemotherapy [ 36 , 37 ], specific symptoms such as fatigue and pain [ 38 , 39 , 40 ], the extent of surgical resection [ 12 , 13 , 40 , 41 ], and psychosocial determinants such as anxiety, depression, self-efficacy, and social support [ 14 ]. Furthermore, evidence on the effects of pre- and/or postoperative exercise training on HRQoL has been limited to reviews that only included preoperative assessments [ 28 , 30 ], have not provided information on important health dimensions such as global quality of life and cancer-specific symptoms such as fatigue [ 34 ], and included non-randomized control trials in the quantitative synthesis [ 27 ], which tend to result in larger effect estimates [ 42 ].…”