Preoperative radiation as part of a multidisciplinary strategy for a medically inoperable patient with a bleeding colon cancer

Abstract

An 84-year-old man with a history of deep vein thrombosis on warfarin and coronary artery disease presented with haematochezia and was diagnosed with an ascending colon cancer. He was short of breath with lower extremity oedema at the initial surgical consultation. Evaluation revealed an acute exacerbation of congestive heart failure, and further workup and treatment were recommended by the cardiology team. After multidisciplinary discussion, he underwent radiation for the control of bleeding, followed by cardiac catheterisation and placement of a bare metal stent. The patient subsequently underwent robotic-assisted right hemicolectomy. Pathology demonstrated a complete response, and the patient recovered uneventfully. He is alive swith no evidence of disease recurrence 12 months after surgery and 18 months after initial diagnosis.

Cone-beam computed tomography-guided online-adaptive radiotherapy for inoperable right colon cancer: First in human

“…Radiotherapy (RT) is not currently part of the management of localised colon cancer due to the lack of clinical benefit and significant toxicity [1] , [2] . Hence, it is only considered a palliative haemostatic treatment in cases of tumoral bleeding [3] . Nevertheless, RT could improve the resection rate and the overall survival in selected patients, according to recent retrospective data [4] , [5] .…”

lncRNA PCA3 plays a key role in colon cancer occurrence and development

“…As one of the clinically most common gastrointestinal tumours, colon cancer is now becoming one of the tumours with the highest incidence [1]. The 5-year survival rate of early-stage colon cancer patients is about 70%.…”