Preoperative steroids triggering diabetic ketoacidosis in the neurosurgical patient

Rahman, Saif Ur; Karmakar, Arunabha; Almustafa, M.; Kumar, Neeraj

doi:10.1016/j.jclinane.2017.12.025

Cited by 9 publications

(10 citation statements)

References 4 publications

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“…Currently, dexamethasone remains one of the few drugs, if not the only drug, that clearly decreases mortality among patients with COVID-19 in critical condition. However, high-dose glucocorticoid therapy, particularly in states of sepsis and inflammation, induces and aggravates hyperglycaemia and metabolic acidosis 2 . Glucocorticoids are the most common reason why people with COVID-19 and diabetes develop life-threatening hyperglycaemic hyperosmolar states.…”

Section: Treatment Of Patients With Covid-19 and Metabolic Diseasementioning

confidence: 99%

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Consequences of the COVID-19 pandemic for patients with metabolic diseases

et al. 2021

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Section: Treatment Of Patients With Covid-19 and Metabolic Diseasementioning

confidence: 99%

“…Given the expectation that the current situation may last for months, or even several years, we must take action so that we remain able to provide evidence-based care for patients with chronic metabolic diseases. ❐ Stefan R. Bornstein 1,2,3,4,5 ✉ , Francesco Rubino 2,6 , Barbara Ludwig 1,3,4,5,7 ,…”

Section: How To Avoid Collateral Damage After the Pandemicmentioning

confidence: 99%

Consequences of the COVID-19 pandemic for patients with metabolic diseases

et al. 2021

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“…This topic has been studied in adult diabetic patients, and the maximum difference in blood glucose at 10 and 24 hours, between those receiving dexamethasone and those not receiving it, was 34 mg/dL and 4 mg/dL, respectively . The incidence of steroid‐induced diabetic ketoacidosis is exceedingly rare . For children with elevated intracranial pressure or adrenal insufficiency, the benefit of exogenous steroid administration outweighs the side effects, and we recommend their administration.…”

Section: Intraoperative Managementmentioning

confidence: 99%

“…25 The incidence of steroid-induced diabetic ketoacidosis is exceedingly rare. 26 For children with elevated intracranial pressure or adrenal insufficiency, the benefit of exogenous steroid administration outweighs the side effects, and we recommend their administration. Intraoperative steroids can also be used for their antiemetic and opioid-sparing effects; for these indications, we ultimately leave it to the discretion of the anesthesiologist, noting that the risk of hyperglycemia is likely small.…”

Section: Intr Aoper Ative Manag Ementmentioning

confidence: 99%

Use of continuous subcutaneous insulin infusion (CSII) therapy in pediatric diabetes patients in the perioperative period

Vanderhoek

Wolf

2019

Pediatric Anesthesia

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Diabetes mellitus is one of the most common endocrinopathies encountered in the perioperative period, and the pediatric population is increasingly using continuous subcutaneous insulin infusions for diabetes management. As these patients present for procedures or surgery requiring anesthesia, the anesthesia provider is charged with the task of managing these pumps perioperatively. Here, we review our experience from a large tertiary care academic medical center and propose recommendations for the perioperative management of children and adolescents with diabetes who use insulin pumps.

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“…Старостина, 2004). Серед дитячого населення саме ДКА є причиною частих госпіталізацій у відділення інтенсивної терапії і складає близько 14,3 % від усіх звернень дітей Туреччини у критичному стані [4]. Якщо ж брати до уваги усі госпіталізації хворих з цукровим діабетом, то на частку діабетичного кетоацидозу як причини госпіталізації у США припадає 1 % від усіх зареєстрованих випадків [5].…”

Section: вступunclassified

Prevalence of Diabetic Ketoacidosis and Its Etiological Factors in the Podillya Region of Ukraine

Nezhinskaya-Astapenko¹,

Sekret²,

Vlasenkо³

2018

Act. Probl. of the Modern Med.

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The diabetes mellitus is one of the most common diseases of the world. It is characterized by a large number of complications, including ketoacidosis and its severe form known as ketoacidosis diabetic coma. The aim was to estimate the causes of the development of diabetic ketoacidosis and the duration of treatment of an acute state in different age groups. Materials and methods. The random sampling of patients included 55 individuals with diabetes mellitus admitted to intensive care unit of the Vinnytsia Regional Highly Specialized Endocrinological Center aged from 9 up to 70 years in an emergency condition of diabetic ketoacidosis during 2009-2014. Average age of patients was 31,58 ± 17,18 years. Patients were divided into 3 clinical groups depending on their age. Diagnosis of diabetic ketoacidosis was made on the basis of the order of the Ministry of Public Health of Ukraine No. 254, 27.04.06. The results obtained were statistically processed by the Russian-language "Statistica 6.1" StatSoft, 1995. Results. In the most of the cases (27,2%) the acute condition was caused by improper diet. Insulin therapy disturbance ranked the 2nd place and made up 21,8% of all cases. 20 % of ketoacidosis cases were a disease debut in first diagnosed diabetes mellitus. An average duration of hospital staying ranged from 2,33 to 3,09 days and depended on clinical form of diabetic ketoacidosis. Conclusions. The commonest causes resulting in the emergency of diabetic ketoacidosis were improper diet, non-compliance with insulin therapy, and first diagnosed diabetes mellitus. The duration of the hospital treatment did not depend on age of patients, however considerably differed according to clinical form of diabetic ketoacidosis.

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Preoperative steroids triggering diabetic ketoacidosis in the neurosurgical patient

Cited by 9 publications

References 4 publications

Consequences of the COVID-19 pandemic for patients with metabolic diseases

Consequences of the COVID-19 pandemic for patients with metabolic diseases

Use of continuous subcutaneous insulin infusion (CSII) therapy in pediatric diabetes patients in the perioperative period

Prevalence of Diabetic Ketoacidosis and Its Etiological Factors in the Podillya Region of Ukraine

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