Preoperative unexpected prolongation of the activated partial thromboplastin time and prothrombin time in adults. Do we need to pursue abnormal results? A retrospective analysis

Biological activities and phenolic compounds of olive oil mill wastewater from Abani, endemic Algerian variety

“…Therefore, this "brine shrimp" larval toxicity test then constitutes a preliminary screening to determine the degree of product toxicity. Indeed, during a toxicological evaluation of plant extracts by this toxicity test, an LC50 value of < 1000 g/mL is considered bioactive 29 .…”

“…The brine shrimp lethality bioassay was performed using the method of 29 . Artemia nauplii were obtained by hatching brine shrimp eggs ( Artemia salina ) in artificial seawater (3.8% NaCl solution) for 48 h. The dissolution of 30 mg of OMW was carried out in 3 mL of artificial seawater containing 20% ​​DMSO to give a concentration of 10 μg/mL.…”

“…This was done by plotting the percent mortality against the logarithm of the extract concentration. The LC 50 value was derived from the regression equation 29 .…”

“…Activating partial thromboplastin time (APTT) was determined according to 29 . A platelet plasma pool comprises a plasma combination from ten healthy, untreated individuals with normal APTT and PT.…”

Extension of patient safety initiatives to perioperative care

“…The COVID-19 outbreak taught that lack of accessibility to surgery is a patient safety issue itself [11]. Low-value surgical indications, unnecessary complementary preoperative tests, and excessive recommendations produce a waste in resources [12] offer no benefits for the patient, induce larger downstream costs [13], delays [14], and can even harm the patient significantly reducing patient's survival [15]. Less-is-more strategies are an essential part of the perioperative approach of the patient safety strategies and need of the agreement between general practitioners, surgeons, and anesthesiologists.…”