Preparation, analysis and application of99mTc-sulphur microcolloid for bone marrow and lymph scintigraphy

Shafiq, Y. F.; Al-Hissoni, M. H. S.; Jassim, M. A.; Azzez, M. A. Abdul

doi:10.1007/bf02035981

Cited by 1 publication

(1 citation statement)

References 6 publications

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“…Similarly, it has got potential uses in serum albumin, pulmonary and renal scintillography, blood flow studies etc., in its lower valency state after its incorporation in appropriate organic or inorganic compounds. [4][5][6] 99Mo-99mTc generator systems have been extensively studied over the last few years and most of the chemical techniques 7-11 such as solvent extraction, chromatography, sublimation, coprecipitation, etc., generally applied to the separation of the daughter, 99mTc, from the parent, 99Mo, are mainly concerned with the higher valency state of the radioisotope. Studies on the separation of 99mTc in its lower valency state is very lacking although it has got some vital applications as such.…”

Section: Introductionmentioning

confidence: 99%

Ascorbic acid as an eluent for99mTc in99Mo−99mTc generator system

Das

1999

J Radioanal Nucl Chem

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A simple chromatographic procedure for clean separation of the important radionuclide, 99mTc, in the equilibrium mixture, 99Mo--99mWc, has been demonstrated. Separation of pure 99mTc has been achieved by preferential extraction of the radioisotope through an anion exchange resin column of Amberlite IRA-410 using Na-ascorbate solution at pH 7 as an el uent. The radiochemical purity of the separated radiotracer has been verified by taking recourse to T-ray spectrometry. The potentiality of the developed procedure lies in the facts that the eluting agent, ascorbic acid, itself has got its own biomedical importance as Vitamin C and the concerned radioisotope can be obtained in both Tc(IV) and Tc(VII) states as per requirement for diagnostic purposes.

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Section: Introductionmentioning

confidence: 99%

Ascorbic acid as an eluent for99mTc in99Mo−99mTc generator system

Das

1999

J Radioanal Nucl Chem

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Preparation, analysis and application of99mTc-sulphur microcolloid for bone marrow and lymph scintigraphy

Cited by 1 publication

References 6 publications

Ascorbic acid as an eluent for99mTc in99Mo−99mTc generator system

Ascorbic acid as an eluent for99mTc in99Mo−99mTc generator system

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