Preparation and Application of Vinamidinium Salts in Organic Synthesis

Abstract

As a kind of important three-carbon building block, vinamidinium salts have been widely used in organic synthesis. In this paper the synthetic methods of vinamidinium salts are summarized, and its applications in the synthesis of aldehydes, aromatic and heterocyclic compounds in recent years are reviewed.

The Application of Vinamidinium Salt to the Synthesis of 3-Chloro-α-carbolines

“…7e,20 Vinamidinium (1,5-diazapentadienium) salts as important three-carbon building blocks have been widely utilized to construct substituted benzenes and heterocyclic compounds. [21][22][23] Herein, we report an efficient synthesis of 3chloro-α-carboline derivatives via a simple procedure from indolinones 2 and the readily available 3-chlorovinamidinium salt 3 24 (Scheme 2).…”