Preparation and characterization of 3D-printed antibacterial hydrogel with benzyl isothiocyanate

Liang, Yunxia; Chitrakar, Bimal; Liu, Zhenbin; Ming, Xujia; Xu, Dongwei; Mo, Haizhen; Shi, Chunyu; Zhu, Xiaolin; Hu, Liangbin; Li, Hongbo

doi:10.18063/ijb.v9i2.671

Cited by 8 publications

(7 citation statements)

References 48 publications

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“…Recently, several commercial medical BC-based materials have been obtained: Biofill ® (Curitiba, Brazil) and Bioprocess ® (Curitiba, Brazil) for burns and ulcer therapy, Gengiflex ® (Curitiba, Brazil) to treat periodontal diseases, Dermafill ® (Londrina, Brazil) for effective wound and ulcer healing, Membracel ® (Curitiba, Brazil) to treat venous leg ulcers and lacerations, xCell ® (New York, NY, USA) for chronic wounds therapy, EpiProtect ® (Royal Wootton Bassett, UK) for burn wounds, and Nanoskin ® incorporated with silver ions (São Carlos, Brazil) [236,253]. BC and xanthan have great potential to be used in medicine as a biomaterial for wound dressing [254][255][256][257][258][259][260][261][262][263][264][265][266], drug delivery systems , and tissue engineering . Recently, many reviews on BC-based materials for biomedical applications have been reported.…”

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

“…The publications on using xanthan to obtain medical materials have appeared relatively recently. So, in the last two decades, researchers have taken an interest in its future use in drug delivery, tissue engineering, as well as biocomposites with regenerative and antibacterial properties [261][262][263][264][265][266][274][275][276][277][278][284][285][286][287][288][289][321][322][323][324][325][326][327][328].…”

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

“…Recently, Unalan et al ( 2023) developed three-dimensional (3D)-printed sodium alginate-xanthan gum hydrogels containing phytotherapeutic agents with antioxidant and antibacterial activity as multifunctional wound dressings [264]. Liang et al (2023) prepared 3D-printed antibacterial hydrogels with benzyl isothiocyanate using xanthan gum, locust bean gum, konjac glucomannan, and carrageenan for burn wound healing [265]. Alves et al produced a thermo-reversible hydrogel composed of xanthan-konjac glucomannan (Figure 5B) [266].…”

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

“…They have also developed an automated active mixing platform which allows for the high-quality preparation of hydrogel bioinks [362]. The use of BC and xanthan as bioinks for 3D printing has tremendous potential in tissue engineering and wound dressings [264,265,328,[363][364][365]. Recently, Unalan et al (2023) and Liang et al (2023) prepared (3D)-printed hydrogels with xanthan for burn wound healing [264,265].…”

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

“…The use of BC and xanthan as bioinks for 3D printing has tremendous potential in tissue engineering and wound dressings [264,265,328,[363][364][365]. Recently, Unalan et al (2023) and Liang et al (2023) prepared (3D)-printed hydrogels with xanthan for burn wound healing [264,265]. Cakmak et al developed a 3D-printed BC/polycaprolactone/gelatin/hydroxyapatite composite scaffold for bone tissue engineering [364].…”

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

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Production of Bacterial Exopolysaccharides: Xanthan and Bacterial Cellulose

Revin,

Liyaskina,

Parchaykina

et al. 2023

IJMS

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Recently, degradable biopolymers have become increasingly important as potential environmentally friendly biomaterials, providing a wide range of applications in various fields. Bacterial exopolysaccharides (EPSs) are biomacromolecules, which due to their unique properties have found applications in biomedicine, foodstuff, textiles, cosmetics, petroleum, pharmaceuticals, nanoelectronics, and environmental remediation. One of the important commercial polysaccharides produced on an industrial scale is xanthan. In recent years, the range of its application has expanded significantly. Bacterial cellulose (BC) is another unique EPS with a rapidly increasing range of applications. Due to the great prospects for their practical application, the development of their highly efficient production remains an important task. The present review summarizes the strategies for the cost-effective production of such important biomacromolecules as xanthan and BC and demonstrates for the first time common approaches to their efficient production and to obtaining new functional materials for a wide range of applications, including wound healing, drug delivery, tissue engineering, environmental remediation, nanoelectronics, and 3D bioprinting. In the end, we discuss present limitations of xanthan and BC production and the line of future research.

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Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

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Production of Bacterial Exopolysaccharides: Xanthan and Bacterial Cellulose

Revin,

Liyaskina,

Parchaykina

et al. 2023

IJMS

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3D Printing‐Based Hydrogel Dressings for Wound Healing

Zhou,

Yu,

You

et al. 2024

Advanced Science

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Skin wounds have become an important issue that affects human health and burdens global medical care. Hydrogel materials similar to the natural extracellular matrix (ECM) are one of the best candidates for ideal wound dressings and the most feasible choices for printing inks. Distinct from hydrogels made by traditional technologies, which lack bionic and mechanical properties, 3D printing can promptly and accurately create hydrogels with complex bioactive structures and the potential to promote tissue regeneration and wound healing. Herein, a comprehensive review of multi‐functional 3D printing‐based hydrogel dressings for wound healing is presented. The review first summarizes the 3D printing techniques for wound hydrogel dressings, including photo‐curing, extrusion, inkjet, and laser‐assisted 3D printing. Then, the properties and design approaches of a series of bioinks composed of natural, synthetic, and composite polymers for 3D printing wound hydrogel dressings are described. Thereafter, the application of multi‐functional 3D printing‐based hydrogel dressings in a variety of wound environments is discussed in depth, including hemostasis, anti‐inflammation, antibacterial, skin appendage regeneration, intelligent monitoring, and machine learning‐assisted therapy. Finally, the challenges and prospects of 3D printing‐based hydrogel dressings for wound healing are presented.

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